Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   P9C33_RS02110 Genome accession   NZ_OX442407
Coordinates   451633..452265 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli isolate pure strain     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 446633..457265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P9C33_RS02085 yhfG 446765..446932 (+) 168 WP_128995334.1 YhfG family protein -
  P9C33_RS02090 fic 446922..447524 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  P9C33_RS02095 pabA 447556..448119 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  P9C33_RS02100 argD 448205..449425 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  P9C33_RS02105 yhfK 449492..451582 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  P9C33_RS02110 crp 451633..452265 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  P9C33_RS02115 yhfA 452567..452971 (+) 405 WP_001148908.1 OsmC family protein -
  P9C33_RS02120 prkB 453026..453895 (-) 870 WP_001274680.1 phosphoribulokinase -
  P9C33_RS02125 yheU 453949..454167 (-) 219 WP_000907085.1 YheU family protein -
  P9C33_RS02130 yheT 454161..455183 (-) 1023 WP_000057356.1 hydrolase -
  P9C33_RS02135 yheS 455183..457096 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=1042045 P9C33_RS02110 WP_000242755.1 451633..452265(-) (crp) [Escherichia coli isolate pure strain]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1042045 P9C33_RS02110 WP_000242755.1 451633..452265(-) (crp) [Escherichia coli isolate pure strain]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGACAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment