Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CF58_RS21275 Genome accession   NZ_CP007392
Coordinates   4362286..4362918 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ST2747     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4357286..4367918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CF58_RS21245 (CF58_27105) yheS 4357449..4359368 (+) 1920 WP_001551739.1 ABC transporter ATP-binding protein -
  CF58_RS21250 (CF58_27110) yheT 4359368..4360390 (+) 1023 WP_001551740.1 hydrolase -
  CF58_RS21255 (CF58_27115) yheU 4360384..4360602 (+) 219 WP_000907085.1 YheU family protein -
  CF58_RS21260 (CF58_27120) prkB 4360656..4361525 (+) 870 WP_001274680.1 phosphoribulokinase -
  CF58_RS21265 (CF58_27125) yhfA 4361580..4361984 (-) 405 WP_001148908.1 OsmC family protein -
  CF58_RS21275 (CF58_27135) crp 4362286..4362918 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CF58_RS21280 (CF58_27140) yhfK 4362969..4365059 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CF58_RS21285 (CF58_27145) argD 4365122..4366345 (-) 1224 WP_001551741.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CF58_RS21290 (CF58_27150) pabA 4366431..4366994 (-) 564 WP_000601862.1 aminodeoxychorismate synthase component 2 -
  CF58_RS21295 (CF58_27155) fic 4367026..4367628 (-) 603 WP_001280634.1 putative adenosine monophosphate-protein transferase Fic -
  CF58_RS21300 yhfG 4367618..4367785 (-) 168 WP_000736851.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=104086 CF58_RS21275 WP_000242755.1 4362286..4362918(+) (crp) [Escherichia coli strain ST2747]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=104086 CF58_RS21275 WP_000242755.1 4362286..4362918(+) (crp) [Escherichia coli strain ST2747]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment