Detailed information NTG1040829

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACDW37_RS24475
• Genome accession: NZ_CP167985
• Coordinates: 5231574..5232911 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 0502d1
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5226574..5237911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACDW37_RS24450 (ACDW37_24450)	pgeF	5226717..5227445 (-)	729	WP_003119426.1	peptidoglycan editing factor PgeF	-
ACDW37_RS24455 (ACDW37_24455)	rluD	5227442..5228404 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACDW37_RS24460 (ACDW37_24460)	-	5228550..5229575 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACDW37_RS24465 (ACDW37_24465)	-	5229732..5229977 (+)	246	WP_003102591.1	PP0621 family protein	-
ACDW37_RS24470 (ACDW37_24470)	pilS	5229967..5231559 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ACDW37_RS24475 (ACDW37_24475)	pilR	5231574..5232911 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACDW37_RS24480 (ACDW37_24480)	thiO	5232957..5234051 (-)	1095	WP_023518092.1	glycine oxidase ThiO	-
ACDW37_RS24485 (ACDW37_24485)	-	5234186..5234695 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
ACDW37_RS24490 (ACDW37_24490)	-	5234801..5235307 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACDW37_RS24495 (ACDW37_24495)	pilV	5235298..5235855 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACDW37_RS24500 (ACDW37_24500)	pilW	5235852..5236676 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACDW37_RS24505 (ACDW37_24505)	pilX	5236673..5237260 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1040829 ACDW37_RS24475 WP_003094694.1 5231574..5232911(+) (pilR) [Pseudomonas aeruginosa strain 0502d1]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1040829 ACDW37_RS24475 WP_003094694.1 5231574..5232911(+) (pilR) [Pseudomonas aeruginosa strain 0502d1]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384