Detailed information NTG1040499

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK17_RS13545
• Genome accession: NZ_CP167943
• Coordinates: 2718111..2718998 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-21
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2713111..2723998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK17_RS13515 (ACCK17_13515)	-	2713130..2713222 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK17_RS13520 (ACCK17_13520)	-	2713330..2713827 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK17_RS13525 (ACCK17_13525)	-	2713837..2714097 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK17_RS13530 (ACCK17_13530)	-	2714479..2714592 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK17_RS13535 (ACCK17_13535)	-	2715251..2717251 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK17_RS13540 (ACCK17_13540)	-	2717248..2718003 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK17_RS13545 (ACCK17_13545)	braS	2718111..2718998 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK17_RS13550 (ACCK17_13550)	braR	2719009..2719674 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK17_RS13555 (ACCK17_13555)	-	2719700..2719900 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK17_RS13560 (ACCK17_13560)	-	2720098..2721522 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK17_RS13565 (ACCK17_13565)	-	2721582..2721683 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK17_RS13570 (ACCK17_13570)	-	2721805..2722260 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK17_RS13575 (ACCK17_13575)	-	2722505..2723266 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1040499 ACCK17_RS13545 WP_000143419.1 2718111..2718998(-) (braS) [Staphylococcus aureus strain CUBIST-21]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1040499 ACCK17_RS13545 WP_000143419.1 2718111..2718998(-) (braS) [Staphylococcus aureus strain CUBIST-21]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997