Detailed information NTG1038115

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB345_RS00680
• Genome accession: NZ_CP167025
• Coordinates: 104540..104974 (+)
• Length: 144 a.a.
• NCBI ID: WP_020904833.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99540..109974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB345_RS00650 (ACB345_00650)	-	101209..101574 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB345_RS00655 (ACB345_00655)	comYA	101667..102605 (+)	939	WP_020904831.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB345_RS00660 (ACB345_00660)	comYB	102541..103575 (+)	1035	WP_226316548.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB345_RS00665 (ACB345_00665)	comYC	103577..103903 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB345_RS00670 (ACB345_00670)	comGD	103878..104306 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ACB345_RS00675 (ACB345_00675)	comGE	104263..104547 (+)	285	WP_011284422.1	competence type IV pilus minor pilin ComGE	-
ACB345_RS00680 (ACB345_00680)	comYF	104540..104974 (+)	435	WP_020904833.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB345_RS00685 (ACB345_00685)	comGG	104958..105284 (+)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
ACB345_RS00690 (ACB345_00690)	comYH	105382..106335 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
ACB345_RS00695 (ACB345_00695)	-	106394..107590 (+)	1197	WP_020904834.1	acetate kinase	-
ACB345_RS00700 (ACB345_00700)	-	107777..108085 (+)	309	Protein_89	hypothetical protein	-
ACB345_RS00705 (ACB345_00705)	proC	108168..108938 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16672.29 Da
• Isoelectric Point: 10.2526

>NTDB_id=1038115 ACB345_RS00680 WP_020904833.1 104540..104974(+) (comYF) [Streptococcus pyogenes strain Isolate]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRNHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1038115 ACB345_RS00680 WP_020904833.1 104540..104974(+) (comYF) [Streptococcus pyogenes strain Isolate]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACTCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAATCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396