Detailed information NTG1037854

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB327_RS02230
• Genome accession: NZ_CP167020
• Coordinates: 418159..419160 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 6
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 413159..424160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB327_RS02205 (ACB327_02205)	-	413833..414516 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
ACB327_RS02210 (ACB327_02210)	-	414727..415653 (-)	927	WP_076639582.1	glycosyltransferase family 2 protein	-
ACB327_RS02215 (ACB327_02215)	-	415798..416175 (-)	378	WP_076639581.1	VOC family protein	-
ACB327_RS02220 (ACB327_02220)	-	416186..416851 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ACB327_RS02225 (ACB327_02225)	-	416900..417985 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
ACB327_RS02230 (ACB327_02230)	ccpA	418159..419160 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB327_RS02235 (ACB327_02235)	-	419291..420289 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ACB327_RS02240 (ACB327_02240)	-	420291..421625 (+)	1335	WP_076639579.1	glycosyltransferase family 4 protein	-
ACB327_RS02245 (ACB327_02245)	thrS	422047..423990 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1037854 ACB327_RS02230 WP_002985680.1 418159..419160(+) (ccpA) [Streptococcus pyogenes strain Isolate 6]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1037854 ACB327_RS02230 WP_002985680.1 418159..419160(+) (ccpA) [Streptococcus pyogenes strain Isolate 6]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559