Detailed information NTG1037839

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB327_RS00680
• Genome accession: NZ_CP167020
• Coordinates: 104893..105327 (+)
• Length: 144 a.a.
• NCBI ID: WP_002986542.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 6
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99893..110327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB327_RS00650 (ACB327_00650)	-	101562..101927 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB327_RS00655 (ACB327_00655)	comYA	102020..102958 (+)	939	WP_002986557.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB327_RS00660 (ACB327_00660)	comYB	102894..103928 (+)	1035	WP_228631569.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB327_RS00665 (ACB327_00665)	comYC	103930..104256 (+)	327	WP_011528161.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB327_RS00670 (ACB327_00670)	comGD	104231..104659 (+)	429	WP_076639399.1	competence type IV pilus minor pilin ComGD	-
ACB327_RS00675 (ACB327_00675)	comGE	104616..104900 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ACB327_RS00680 (ACB327_00680)	comYF	104893..105327 (+)	435	WP_002986542.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB327_RS00685 (ACB327_00685)	comGG	105311..105637 (+)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
ACB327_RS00690 (ACB327_00690)	comYH	105735..106688 (+)	954	WP_129322573.1	class I SAM-dependent methyltransferase	Machinery gene
ACB327_RS00695 (ACB327_00695)	-	106747..107943 (+)	1197	WP_020904834.1	acetate kinase	-
ACB327_RS00700 (ACB327_00700)	-	108130..108438 (+)	309	Protein_89	hypothetical protein	-
ACB327_RS00705 (ACB327_00705)	proC	108521..109291 (-)	771	WP_076639397.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16573.20 Da
• Isoelectric Point: 10.3584

>NTDB_id=1037839 ACB327_RS00680 WP_002986542.1 104893..105327(+) (comYF) [Streptococcus pyogenes strain Isolate 6]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1037839 ACB327_RS00680 WP_002986542.1 104893..105327(+) (comYF) [Streptococcus pyogenes strain Isolate 6]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396