Detailed information NTG1037456

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB343_RS00680
• Genome accession: NZ_CP167012
• Coordinates: 104215..104649 (+)
• Length: 144 a.a.
• NCBI ID: WP_002992738.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 17
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99215..109649

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB343_RS00650 (ACB343_00650)	-	100884..101249 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB343_RS00655 (ACB343_00655)	comYA	101342..102280 (+)	939	WP_011284420.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB343_RS00660 (ACB343_00660)	comYB	102216..103250 (+)	1035	WP_227868694.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB343_RS00665 (ACB343_00665)	comYC	103252..103578 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB343_RS00670 (ACB343_00670)	comGD	103553..103981 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ACB343_RS00675 (ACB343_00675)	comGE	103938..104222 (+)	285	WP_011284422.1	competence type IV pilus minor pilin ComGE	-
ACB343_RS00680 (ACB343_00680)	comYF	104215..104649 (+)	435	WP_002992738.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB343_RS00685 (ACB343_00685)	comGG	104633..104959 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
ACB343_RS00690 (ACB343_00690)	comYH	105057..106010 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
ACB343_RS00695 (ACB343_00695)	-	106069..107265 (+)	1197	WP_011284424.1	acetate kinase	-
ACB343_RS00700 (ACB343_00700)	-	107452..107760 (+)	309	WP_011284425.1	hypothetical protein	-
ACB343_RS00705 (ACB343_00705)	proC	107843..108613 (-)	771	WP_011284426.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16645.27 Da
• Isoelectric Point: 10.2526

>NTDB_id=1037456 ACB343_RS00680 WP_002992738.1 104215..104649(+) (comYF) [Streptococcus pyogenes strain Isolate 17]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1037456 ACB343_RS00680 WP_002992738.1 104215..104649(+) (comYF) [Streptococcus pyogenes strain Isolate 17]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396