Detailed information NTG1037346

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB333_RS00615
• Genome accession: NZ_CP167010
• Coordinates: 98718..99152 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 20
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 93718..104152

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB333_RS00585 (ACB333_00585)	-	95387..95752 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB333_RS00590 (ACB333_00590)	comYA	95845..96783 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB333_RS00595 (ACB333_00595)	comYB	96719..97753 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB333_RS00600 (ACB333_00600)	comYC	97755..98081 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB333_RS00605 (ACB333_00605)	comGD	98056..98484 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ACB333_RS00610 (ACB333_00610)	comGE	98441..98725 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ACB333_RS00615 (ACB333_00615)	comYF	98718..99152 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB333_RS00620 (ACB333_00620)	comGG	99136..99462 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
ACB333_RS00625 (ACB333_00625)	comYH	99560..100513 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
ACB333_RS00630 (ACB333_00630)	-	100572..101768 (+)	1197	WP_010921803.1	acetate kinase	-
ACB333_RS00635 (ACB333_00635)	-	101955..102263 (+)	309	WP_010921804.1	hypothetical protein	-
ACB333_RS00640 (ACB333_00640)	proC	102346..103116 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=1037346 ACB333_RS00615 WP_010921800.1 98718..99152(+) (comYF) [Streptococcus pyogenes strain Isolate 20]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1037346 ACB333_RS00615 WP_010921800.1 98718..99152(+) (comYF) [Streptococcus pyogenes strain Isolate 20]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389