Detailed information NTG1037327

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB352_RS07625
• Genome accession: NZ_CP167009
• Coordinates: 1491407..1492408 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 22
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1486407..1497408

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB352_RS07610 (ACB352_07610)	thrS	1486577..1488520 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
ACB352_RS07615 (ACB352_07615)	-	1488942..1490276 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
ACB352_RS07620 (ACB352_07620)	-	1490278..1491276 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
ACB352_RS07625 (ACB352_07625)	ccpA	1491407..1492408 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB352_RS07630 (ACB352_07630)	-	1492582..1493667 (+)	1086	WP_011284589.1	aminopeptidase P family protein	-
ACB352_RS07635 (ACB352_07635)	-	1493716..1494381 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ACB352_RS07640 (ACB352_07640)	-	1494392..1494769 (+)	378	WP_002985686.1	VOC family protein	-
ACB352_RS07645 (ACB352_07645)	-	1494914..1495840 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
ACB352_RS07650 (ACB352_07650)	-	1496051..1496734 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1037327 ACB352_RS07625 WP_002985680.1 1491407..1492408(-) (ccpA) [Streptococcus pyogenes strain Isolate 22]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1037327 ACB352_RS07625 WP_002985680.1 1491407..1492408(-) (ccpA) [Streptococcus pyogenes strain Isolate 22]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559