Detailed information NTG1037128

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB360_RS00620
• Genome accession: NZ_CP167006
• Coordinates: 98490..98924 (+)
• Length: 144 a.a.
• NCBI ID: WP_002987783.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 26
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 93490..103924

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB360_RS00590 (ACB360_00590)	-	95159..95524 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB360_RS00595 (ACB360_00595)	comYA	95617..96555 (+)	939	WP_002987773.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB360_RS00600 (ACB360_00600)	comYB	96491..97525 (+)	1035	WP_223845212.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB360_RS00605 (ACB360_00605)	comYC	97527..97853 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB360_RS00610 (ACB360_00610)	comGD	97828..98256 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ACB360_RS00615 (ACB360_00615)	comGE	98213..98497 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ACB360_RS00620 (ACB360_00620)	comYF	98490..98924 (+)	435	WP_002987783.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB360_RS00625 (ACB360_00625)	comGG	98908..99234 (+)	327	WP_002987787.1	competence type IV pilus minor pilin ComGG	-
ACB360_RS00630 (ACB360_00630)	comYH	99332..100285 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
ACB360_RS00635 (ACB360_00635)	-	100344..101540 (+)	1197	WP_002987791.1	acetate kinase	-
ACB360_RS00640 (ACB360_00640)	-	101727..102035 (+)	309	WP_011284425.1	hypothetical protein	-
ACB360_RS00645 (ACB360_00645)	proC	102118..102888 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16585.23 Da
• Isoelectric Point: 10.2064

>NTDB_id=1037128 ACB360_RS00620 WP_002987783.1 98490..98924(+) (comYF) [Streptococcus pyogenes strain Isolate 26]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1037128 ACB360_RS00620 WP_002987783.1 98490..98924(+) (comYF) [Streptococcus pyogenes strain Isolate 26]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396