Detailed information NTG1037087

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB340_RS02350
• Genome accession: NZ_CP167005
• Coordinates: 429744..430745 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 27
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 424744..435745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB340_RS02325 (ACB340_02325)	-	425418..426101 (-)	684	WP_012560521.1	DUF969 domain-containing protein	-
ACB340_RS02330 (ACB340_02330)	-	426312..427238 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ACB340_RS02335 (ACB340_02335)	-	427383..427760 (-)	378	WP_115224547.1	VOC family protein	-
ACB340_RS02340 (ACB340_02340)	-	427771..428436 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ACB340_RS02345 (ACB340_02345)	-	428485..429570 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
ACB340_RS02350 (ACB340_02350)	ccpA	429744..430745 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB340_RS02355 (ACB340_02355)	-	430876..431874 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ACB340_RS02360 (ACB340_02360)	-	431876..433210 (+)	1335	WP_115224548.1	glycosyltransferase family 4 protein	-
ACB340_RS02365 (ACB340_02365)	thrS	433632..435575 (+)	1944	WP_111677101.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1037087 ACB340_RS02350 WP_002985680.1 429744..430745(+) (ccpA) [Streptococcus pyogenes strain Isolate 27]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1037087 ACB340_RS02350 WP_002985680.1 429744..430745(+) (ccpA) [Streptococcus pyogenes strain Isolate 27]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCATAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559