Detailed information NTG1037054

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB354_RS07825
• Genome accession: NZ_CP167004
• Coordinates: 1486945..1487946 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 28
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1481945..1492946

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB354_RS07810 (ACB354_07815)	thrS	1482115..1484058 (-)	1944	WP_011184277.1	threonine--tRNA ligase	-
ACB354_RS07815 (ACB354_07820)	-	1484480..1485814 (-)	1335	WP_011184276.1	glycosyltransferase family 4 protein	-
ACB354_RS07820 (ACB354_07825)	-	1485816..1486814 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ACB354_RS07825 (ACB354_07830)	ccpA	1486945..1487946 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB354_RS07830 (ACB354_07835)	-	1488120..1489205 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
ACB354_RS07835 (ACB354_07840)	-	1489254..1489919 (+)	666	WP_011184275.1	NAD(P)H-dependent oxidoreductase	-
ACB354_RS07840 (ACB354_07845)	-	1489930..1490307 (+)	378	WP_002985686.1	VOC family protein	-
ACB354_RS07845 (ACB354_07850)	-	1490452..1491378 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
ACB354_RS07850 (ACB354_07855)	-	1491589..1492272 (+)	684	WP_021340135.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1037054 ACB354_RS07825 WP_002985680.1 1486945..1487946(-) (ccpA) [Streptococcus pyogenes strain Isolate 28]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1037054 ACB354_RS07825 WP_002985680.1 1486945..1487946(-) (ccpA) [Streptococcus pyogenes strain Isolate 28]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGATTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559