Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   ACB354_RS01350 Genome accession   NZ_CP167004
Coordinates   251793..253763 (+) Length   656 a.a.
NCBI ID   WP_011017333.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 28     
Function   internalize XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 250520..251548 251793..253763 flank 245


Gene organization within MGE regions


Location: 250520..253763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS01345 (ACB354_01345) - 250520..251548 (-) 1029 WP_326623038.1 IS30-like element IS1239 family transposase -
  ACB354_RS01350 (ACB354_01350) amiA 251793..253763 (+) 1971 WP_011017333.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 72060.51 Da        Isoelectric Point: 5.1964

>NTDB_id=1037021 ACB354_RS01350 WP_011017333.1 251793..253763(+) (amiA) [Streptococcus pyogenes strain Isolate 28]
MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLV
PSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNENYWD
AKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLSGDIRHLTWNLNRTSFKNTKK
DPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKLGDEWKDVN
LADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETSTHE
AQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDN
DARYKAYAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVTAKQYEKAKEKWMKAKA
KSNAKYAEKLADHVEK

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=1037021 ACB354_RS01350 WP_011017333.1 251793..253763(+) (amiA) [Streptococcus pyogenes strain Isolate 28]
ATGAAGAAAAGTAAATGGTTGGCAGCTGTAAGTGTTGCGATCTTGTCAGTATCCGCTTTGGCAGCTTGTGGTAATAAAAA
TGCTTCAGGTGGCTCAGAAGCTACAAAAACCTACAAGTACGTTTTTGTTAACGATCCAAAATCATTGGATTATATTTTGA
CTAATGGCGGTGGAACGACTGATGTGATAACACAAATGGTTGATGGTCTTTTGGAAAACGATGAGTATGGTAATTTAGTA
CCATCACTTGCTAAAGATTGGAAGGTTTCAAAAGACGGTCTGACTTATACTTATACTCTTCGCGATGGTGTCTCTTGGTA
TACGGCTGATGGTGAAGAATATGCCCCAGTAACAGCAGAAGATTTTGTGACTGGTTTGAAGCACGCGGTTGACGATAAAT
CAGATGCTCTTTACGTTGTTGAAGATTCAATAAAAAACTTAAAGGCTTACCAAAATGGTGAAGTAGATTTTAAAGAAGTT
GGTGTCAAAGCCCTTGACGATAAAACTGTTCAGTATACTTTGAACAAGCCTGAAAGCTACTGGAATTCAAAAACAACTTA
TAGTGTGCTTTTCCCAGTTAATGCGAAATTTTTGAAGTCAAAAGGTAAAGATTTTGGTACAACCGATCCATCATCAATCC
TTGTTAATGGTGCTTACTTCTTGAGCGCCTTCACCTCAAAATCATCTATGGAATTCCATAAAAATGAAAACTACTGGGAT
GCTAAGAATGTTGGGATAGAATCTGTTAAATTGACTTACTCAGATGGTTCAGACCCAGGTTCGTTCTACAAGAACTTTGA
CAAGGGTGAGTTCAGCGTTGCACGACTTTACCCAAATGACCCTACCTACAAATCAGCTAAGAAAAACTATGCTGATAACA
TTACTTACGGAATGTTGAGTGGAGATATCCGTCATTTAACATGGAATTTGAACCGTACTTCTTTCAAAAACACTAAGAAA
GACCCTGCACAACAAGATGCCGGTAAGAAAGCTCTTAACAACAAGGATTTTCGTCAAGCTATTCAGTTTGCTTTTGACCG
AGCGTCATTCCAAGCCCAAACTGCAGGTCAAGATGCTAAAACAAAAGCCTTACGTAACATGCTTGTCCCACCAACATTTG
TGACCATTGGAGAAAGTGATTTTGGTTCAGAAGTTGAAAAGGAAATGGCAAAACTTGGTGATGAATGGAAAGACGTTAAC
TTAGCTGATGCTCAAGATGGTTTCTATAATCCTGAAAAAGCAAAAGCTGAGTTTGCAAAAGCCAAAGAAGCTTTGACAGC
TGAAGGTGTAACCTTCCCAGTTCAATTAGATTACCCTGTTGACCAAGCAAACGCAGCAACTGTTCAGGAAGCCCAGTCTT
TCAAACAATCTGTTGAAGCATCTCTTGGTAAAGAAAATGTCATTGTCAATGTTCTTGAAACAGAAACATCAACTCACGAA
GCCCAAGGCTTCTATGCTGAGACCCCAGAACAACAAGACTACGATATCATTTCATCATGGTGGGGACCAGACTATCAAGA
TCCACGGACCTACCTTGACATCATGAGTCCAGTAGGTGGTGGATCTGTTATCCAAAAACTTGGAATCAAAGCAGGTCAAA
ATAAGGATGTTGTGGCAGCTGCAGGCCTTGATACCTACCAAACTCTTCTTGATGAAGCAGCAGCAATTACAGACGACAAC
GATGCGCGCTATAAAGCTTACGCAAAAGCACAAGCCTACCTTACAGATAATGCCGTAGATATTCCAGTTGTGGCATTGGG
TGGCACTCCACGAGTTACTAAAGCCGTTCCATTTAGCGGGGGCTTCTCTTGGGCAGGGTCTAAAGGTCCTCTAGCATATA
AAGGAATGAAACTTCAAGACAAACCTGTCACAGCAAAACAATACGAAAAAGCAAAAGAAAAATGGATGAAAGCAAAGGCT
AAGTCAAATGCAAAATATGCTGAGAAGTTAGCTGATCACGTTGAAAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(79-515)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

51.135

100

0.515
  amiA3 Streptococcus thermophilus LMG 18311

49.849

100

0.503
  amiA3 Streptococcus thermophilus LMD-9

49.547

100

0.5

Multiple sequence alignment