Detailed information NTG1036959

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB329_RS00680
• Genome accession: NZ_CP167003
• Coordinates: 104717..105151 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 29
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99717..110151

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB329_RS00650 (ACB329_00650)	-	101386..101751 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB329_RS00655 (ACB329_00655)	comYA	101844..102782 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB329_RS00660 (ACB329_00660)	comYB	102718..103752 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB329_RS00665 (ACB329_00665)	comYC	103754..104080 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB329_RS00670 (ACB329_00670)	comGD	104055..104483 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ACB329_RS00675 (ACB329_00675)	comGE	104440..104724 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ACB329_RS00680 (ACB329_00680)	comYF	104717..105151 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB329_RS00685 (ACB329_00685)	comGG	105135..105461 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
ACB329_RS00690 (ACB329_00690)	comYH	105559..106512 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
ACB329_RS00695 (ACB329_00695)	-	106571..107767 (+)	1197	WP_010921803.1	acetate kinase	-
ACB329_RS00700 (ACB329_00700)	-	107954..108262 (+)	309	WP_010921804.1	hypothetical protein	-
ACB329_RS00705 (ACB329_00705)	proC	108345..109115 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=1036959 ACB329_RS00680 WP_010921800.1 104717..105151(+) (comYF) [Streptococcus pyogenes strain Isolate 29]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1036959 ACB329_RS00680 WP_010921800.1 104717..105151(+) (comYF) [Streptococcus pyogenes strain Isolate 29]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389