Detailed information NTG1036751

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB350_RS02235
• Genome accession: NZ_CP166999
• Coordinates: 423639..424640 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 34
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 418639..429640

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB350_RS02210 (ACB350_02210)	-	419313..419996 (-)	684	WP_030127180.1	DUF969 domain-containing protein	-
ACB350_RS02215 (ACB350_02215)	-	420207..421133 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ACB350_RS02220 (ACB350_02220)	-	421278..421655 (-)	378	WP_002985686.1	VOC family protein	-
ACB350_RS02225 (ACB350_02225)	-	421666..422331 (-)	666	WP_030127181.1	NAD(P)H-dependent oxidoreductase	-
ACB350_RS02230 (ACB350_02230)	-	422380..423465 (-)	1086	WP_030127182.1	aminopeptidase P family protein	-
ACB350_RS02235 (ACB350_02235)	ccpA	423639..424640 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB350_RS02240 (ACB350_02240)	-	424771..425769 (+)	999	WP_030127183.1	glycosyltransferase family 4 protein	-
ACB350_RS02245 (ACB350_02245)	-	425771..427105 (+)	1335	WP_030127184.1	glycosyltransferase family 4 protein	-
ACB350_RS02250 (ACB350_02250)	thrS	427527..429470 (+)	1944	WP_030127185.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1036751 ACB350_RS02235 WP_002985680.1 423639..424640(+) (ccpA) [Streptococcus pyogenes strain Isolate 34]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1036751 ACB350_RS02235 WP_002985680.1 423639..424640(+) (ccpA) [Streptococcus pyogenes strain Isolate 34]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCTAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559