Detailed information NTG1036699

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB356_RS02235
• Genome accession: NZ_CP166998
• Coordinates: 419321..420322 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 35
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 414321..425322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB356_RS02210 (ACB356_02210)	-	414995..415678 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
ACB356_RS02215 (ACB356_02215)	-	415889..416815 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
ACB356_RS02220 (ACB356_02220)	-	416960..417337 (-)	378	WP_002985686.1	VOC family protein	-
ACB356_RS02225 (ACB356_02225)	-	417348..418013 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ACB356_RS02230 (ACB356_02230)	-	418062..419147 (-)	1086	WP_002990707.1	aminopeptidase P family protein	-
ACB356_RS02235 (ACB356_02235)	ccpA	419321..420322 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB356_RS02240 (ACB356_02240)	-	420453..421451 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
ACB356_RS02245 (ACB356_02245)	-	421453..422787 (+)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
ACB356_RS02250 (ACB356_02250)	thrS	423209..425152 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1036699 ACB356_RS02235 WP_002985680.1 419321..420322(+) (ccpA) [Streptococcus pyogenes strain Isolate 35]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1036699 ACB356_RS02235 WP_002985680.1 419321..420322(+) (ccpA) [Streptococcus pyogenes strain Isolate 35]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559