Detailed information NTG1036684

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB356_RS00685
• Genome accession: NZ_CP166998
• Coordinates: 104490..104924 (+)
• Length: 144 a.a.
• NCBI ID: WP_002987783.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 35
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99490..109924

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB356_RS00655 (ACB356_00655)	-	101159..101524 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB356_RS00660 (ACB356_00660)	comYA	101617..102555 (+)	939	WP_002987773.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB356_RS00665 (ACB356_00665)	comYB	102491..103525 (+)	1035	WP_223845212.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB356_RS00670 (ACB356_00670)	comYC	103527..103853 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB356_RS00675 (ACB356_00675)	comGD	103828..104256 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ACB356_RS00680 (ACB356_00680)	comGE	104213..104497 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ACB356_RS00685 (ACB356_00685)	comYF	104490..104924 (+)	435	WP_002987783.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB356_RS00690 (ACB356_00690)	comGG	104908..105234 (+)	327	WP_002987787.1	competence type IV pilus minor pilin ComGG	-
ACB356_RS00695 (ACB356_00695)	comYH	105332..106285 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
ACB356_RS00700 (ACB356_00700)	-	106344..107540 (+)	1197	WP_002987791.1	acetate kinase	-
ACB356_RS00705 (ACB356_00705)	-	107727..108035 (+)	309	WP_011284425.1	hypothetical protein	-
ACB356_RS00710 (ACB356_00710)	proC	108118..108888 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16585.23 Da
• Isoelectric Point: 10.2064

>NTDB_id=1036684 ACB356_RS00685 WP_002987783.1 104490..104924(+) (comYF) [Streptococcus pyogenes strain Isolate 35]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1036684 ACB356_RS00685 WP_002987783.1 104490..104924(+) (comYF) [Streptococcus pyogenes strain Isolate 35]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396