Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   LSO74_RS03455 Genome accession   NZ_OV040719
Coordinates   658231..658737 (+) Length   168 a.a.
NCBI ID   WP_005656467.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 3655 isolate 3655     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 653231..663737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LSO74_RS03435 (KRLU3655_LOCUS646) - 653343..653672 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  LSO74_RS03440 (KRLU3655_LOCUS647) - 653825..654670 (-) 846 WP_005656472.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  LSO74_RS03445 (KRLU3655_LOCUS648) - 654743..657337 (-) 2595 WP_005656471.1 penicillin-binding protein 1A -
  LSO74_RS03450 (KRLU3655_LOCUS649) comA 657433..658230 (+) 798 WP_005656469.1 pilus assembly protein PilM Machinery gene
  LSO74_RS03455 (KRLU3655_LOCUS650) comB 658231..658737 (+) 507 WP_005656467.1 competence protein ComB Machinery gene
  LSO74_RS03460 (KRLU3655_LOCUS651) comC 658734..659255 (+) 522 WP_005656465.1 competence protein ComC Machinery gene
  LSO74_RS03465 (KRLU3655_LOCUS652) comD 659252..659665 (+) 414 WP_005656464.1 pilus assembly protein PilP Machinery gene
  LSO74_RS03470 (KRLU3655_LOCUS653) comE 659675..661012 (+) 1338 WP_005659796.1 type IV pilus secretin PilQ family protein Machinery gene
  LSO74_RS03475 (KRLU3655_LOCUS654) - 661025..661711 (+) 687 WP_005656460.1 ComF family protein -
  LSO74_RS03480 (KRLU3655_LOCUS655) nfuA 661787..662383 (+) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -
  LSO74_RS03485 (KRLU3655_LOCUS656) nudC 662450..663244 (+) 795 WP_005656457.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19752.67 Da        Isoelectric Point: 9.4939

>NTDB_id=1035761 LSO74_RS03455 WP_005656467.1 658231..658737(+) (comB) [Haemophilus influenzae strain 3655 isolate 3655]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQKSFEQLNQQLHKTTMRIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=1035761 LSO74_RS03455 WP_005656467.1 658231..658737(+) (comB) [Haemophilus influenzae strain 3655 isolate 3655]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAGGCACAGCAAA
AGTCGTTTGAACAACTTAATCAACAGCTTCATAAAACTACCATGCGAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGCTTGGAAGGTAACGCACAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

98.81

100

0.988
  comB Haemophilus influenzae Rd KW20

98.81

100

0.988

Multiple sequence alignment