Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   STAB904_RS08415 Genome accession   NZ_CP007241
Coordinates   1729933..1731915 (-) Length   660 a.a.
NCBI ID   WP_038434338.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1E1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1724933..1736915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAB904_RS08390 (STAB904_09425) recA 1724969..1726105 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  STAB904_RS08395 (STAB904_09430) cinA 1726194..1727465 (-) 1272 WP_038434334.1 competence/damage-inducible protein A Machinery gene
  STAB904_RS08400 (STAB904_09435) - 1727534..1728094 (-) 561 WP_023611248.1 DNA-3-methyladenine glycosylase I -
  STAB904_RS08405 (STAB904_09440) ruvA 1728104..1728700 (-) 597 WP_038434336.1 Holliday junction branch migration protein RuvA Machinery gene
  STAB904_RS08410 (STAB904_09445) - 1728702..1729922 (-) 1221 WP_038434337.1 MDR family MFS transporter -
  STAB904_RS08415 (STAB904_09450) hexB 1729933..1731915 (-) 1983 WP_038434338.1 DNA mismatch repair endonuclease MutL Machinery gene
  STAB904_RS08420 (STAB904_09455) hexA 1732044..1734599 (-) 2556 WP_038434339.1 DNA mismatch repair protein MutS Machinery gene
  STAB904_RS09615 - 1734586..1734938 (-) 353 Protein_1616 YlbF family regulator -
  STAB904_RS08430 (STAB904_09465) argR 1734935..1735372 (-) 438 WP_002982171.1 arginine repressor -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74315.89 Da        Isoelectric Point: 5.8707

>NTDB_id=103553 STAB904_RS08415 WP_038434338.1 1729933..1731915(-) (hexB) [Streptococcus pyogenes strain 1E1]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTSDLRQAIAGIYGLNTTKKMLAISNADLDFEVSGYVSLP
ELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAVDNSVKVEK
VELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLENEGQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=103553 STAB904_RS08415 WP_038434338.1 1729933..1731915(-) (hexB) [Streptococcus pyogenes strain 1E1]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCGTTGAAATTGAAGAGTCTGGCCTTAAGA
TGATACAGGTTACAGACAACGGTGAGGGAATGTCTCATGAAGATTTACCTTTAAGTCTGCGTCGCCACGCTACTAGTAAA
ATTAAGAGTCAGAGTGATTTGTTTAGAATTAGAACACTTGGCTTCCGTGGAGAGGCTTTACCGTCTGTTGCCTCTATCAG
TAAAATCACGATAAAAACAGCAACAAAAGAAGTCACTCACGGTTCTCTTCTTATAGCTACTGGTGGGGAAATTGAGACAC
TTGAAGCGATCTCAACTCCTACTGGAACCAAAATTAAGGTTGAAAACCTTTTTTACAACACGCCTGCTCGTCTCAAATAT
ATGAAAAGTTTACAGGCAGAATTAGCTCACATTGTAGATGTGGTCAACCGGTTGAGTTTGGCACATCCAGAAGTTGCTTT
CACACTGATTAGTGATGGTCGCCAATTAACTCAGACATCAGGAACTAGCGATTTACGCCAAGCAATTGCAGGGATTTATG
GTTTGAATACTACCAAAAAAATGCTGGCTATCTCTAATGCTGATTTGGATTTTGAAGTTTCCGGCTATGTTAGCTTGCCA
GAGTTGACACGCGCCAACCGTAATTACATGACGATTTTGGTTAATGGGCGTTACATCAAGAATTTCTTGCTTAATCGAGC
AATTCTTGATGGTTACGGTTCTAAGCTCATGGTTGGACGTTTCCCAATTGTTGTGATTGATATTCAGATTGATCCCTATT
TGGCCGATGTCAATGTTCACCCCACAAAACAAGAGGTTCGTATTTCAAAAGAGCGTGAATTAATGGCTTTAATTAGCACG
GCTATTTCAGAGAGTCTTAAGGAACAAGATTTGATTCCAGATGCTCTGGAAAACTTAGCCAAATCAAGCACACGACATTT
CTCTAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGACTTTATTATGATCCTCAAAAGAATGACTTTTTTGTCA
AAGAGTCGGCTGTCTCGGAAAAAATACCTGAAACTGATTTTTATTCCGGCGCTGTTGACAACAGTGTAAAGGTTGAAAAA
GTAGAGCTGTTACCCCACTCAGAAGAAGTTATAGGACCTTCTTCGGTTAAACACGCAAGTCGTCCCCAGAATACCTTTAC
CGAGACTGATCATCCTAATCTTGACTTAAAAAACAGACAAAAGTTATCTCAAATGCTAACCCGTTTGGAAAATGAAGGGC
AATCAGTGTTTCCCGAATTGGATTATTTTGGTCAGATGCACGGAACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATAATTGACCAACACGCTGCCCAGGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAATTGTTGGTGCCCTATTTGTTTGAGTTTTCTGGTTCTGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCTTAGAAGTTTATGGGCACAATACTTTCATTTTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTATCTATTAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTGGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTATTGATTAATTTTAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGAATTCAAGAAAATCACACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

66.767

100

0.67

Multiple sequence alignment