Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACAF57_RS03790 Genome accession   NZ_CP166700
Coordinates   747392..748531 (-) Length   379 a.a.
NCBI ID   WP_370673172.1    Uniprot ID   -
Organism   Leuconostoc lactis strain PG-3     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 742392..753531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAF57_RS03750 (ACAF57_03750) - 742656..742991 (-) 336 WP_370673170.1 PadR family transcriptional regulator -
  ACAF57_RS03765 (ACAF57_03765) - 743385..743771 (-) 387 WP_077281973.1 DUF6508 domain-containing protein -
  ACAF57_RS03770 (ACAF57_03770) - 743817..744920 (-) 1104 WP_270746701.1 AI-2E family transporter -
  ACAF57_RS03775 (ACAF57_03775) mutY 744926..745942 (-) 1017 WP_370673171.1 A/G-specific adenine glycosylase -
  ACAF57_RS03780 (ACAF57_03780) - 746066..746209 (+) 144 WP_010000998.1 hypothetical protein -
  ACAF57_RS03785 (ACAF57_03785) rlmH 746282..746761 (-) 480 WP_010000997.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACAF57_RS03790 (ACAF57_03790) htrA 747392..748531 (-) 1140 WP_370673172.1 S1C family serine protease Regulator
  ACAF57_RS03795 (ACAF57_03795) yycI 748594..749370 (-) 777 WP_370673173.1 two-component system regulatory protein YycI -
  ACAF57_RS03800 (ACAF57_03800) yycH 749396..750706 (-) 1311 WP_146976129.1 two-component system activity regulator YycH -
  ACAF57_RS03805 (ACAF57_03805) walK 750696..752567 (-) 1872 WP_370673174.1 cell wall metabolism sensor histidine kinase WalK -
  ACAF57_RS03810 (ACAF57_03810) yycF 752663..753370 (-) 708 WP_029510319.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39342.77 Da        Isoelectric Point: 9.1970

>NTDB_id=1035009 ACAF57_RS03790 WP_370673172.1 747392..748531(-) (htrA) [Leuconostoc lactis strain PG-3]
MADKSLTKIIVTGAVAGVLGGGAMLYGQRGLEDMQQSQQKVTTKADKTVTIAKDATATSAYNKVSDAVVSVLNFSQTGKD
TFQEASEGSGVIYKKSGDAAYVVTNNHVINGAAQIQVMLHDGQKVTATLVGKDAMTDLAVLKIAADKVTTTAAFGDSNKI
QVGQKVLAIGSPLGSQYASSVTEGIISAKKRLVESSSEDGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSASGTSVEGMGFAIPSNQVVDIVNKLVKYGQVTRPAIGIGLVELSAVTVDDQKSLLKIPDTVKGGVVVMSLIPNGPAAK
AGIQKYDVITGIDGKTVTGQADLREELYKHDLNDTVTITYYHQAEKKTVKVKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=1035009 ACAF57_RS03790 WP_370673172.1 747392..748531(-) (htrA) [Leuconostoc lactis strain PG-3]
ATGGCAGATAAATCATTAACAAAAATTATCGTAACCGGCGCAGTTGCTGGCGTTCTTGGTGGTGGGGCAATGTTGTATGG
GCAGCGCGGCTTAGAAGATATGCAACAATCACAACAAAAAGTCACCACCAAGGCTGATAAGACGGTGACAATTGCCAAGG
ATGCAACGGCGACTTCAGCTTACAATAAAGTGTCAGATGCGGTTGTTTCTGTGTTGAATTTCTCTCAAACAGGCAAAGAT
ACGTTTCAAGAAGCATCTGAAGGTTCAGGCGTGATTTACAAGAAGTCTGGGGATGCGGCCTATGTGGTGACGAATAATCA
CGTGATTAACGGAGCAGCTCAAATTCAAGTCATGTTACATGACGGGCAAAAGGTGACGGCTACGTTGGTTGGAAAAGATG
CCATGACGGACTTAGCGGTGTTAAAGATTGCTGCCGATAAGGTTACCACAACGGCAGCATTTGGTGATTCCAATAAGATC
CAAGTAGGTCAGAAAGTTTTGGCTATTGGCTCGCCGTTAGGGTCACAATATGCGTCATCGGTGACAGAAGGGATTATTTC
GGCTAAGAAGCGTTTGGTGGAGTCTTCTTCTGAAGATGGGCAAAATTATGGGGGCTCAACGGTTATTCAAACCGATGCGG
CCATTAACCCTGGTAATTCCGGTGGTCCATTAATTAATTTTGCTGGCCAAGTGATTGGGATTAACTCAATGAAACTCTCT
TCTTCTGCATCTGGCACGAGTGTTGAAGGGATGGGATTTGCTATTCCGTCAAATCAAGTGGTGGATATTGTTAATAAGTT
GGTCAAGTATGGCCAAGTGACGCGTCCAGCTATTGGCATTGGATTAGTTGAATTATCAGCTGTGACGGTTGATGACCAAA
AGTCGCTGTTGAAGATCCCAGATACAGTTAAGGGCGGCGTTGTTGTCATGAGTTTGATCCCTAATGGACCAGCGGCTAAA
GCTGGTATTCAGAAATACGACGTAATTACTGGAATTGATGGTAAAACCGTGACGGGGCAAGCTGACTTGCGTGAAGAACT
ATATAAGCATGATCTTAATGATACGGTCACAATTACTTATTATCACCAAGCAGAGAAAAAGACTGTTAAAGTTAAATTAA
CACAAAAATTAGGAAGTTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(88-234)

PDZ domain (PDZ_2)

(276-373)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.273

100

0.48
  htrA Streptococcus gordonii str. Challis substr. CH1

46.966

100

0.47
  htrA Streptococcus pneumoniae D39

50.595

88.654

0.449
  htrA Streptococcus pneumoniae TIGR4

50.595

88.654

0.449
  htrA Streptococcus pneumoniae R6

50.595

88.654

0.449
  htrA Streptococcus pneumoniae Rx1

50.595

88.654

0.449
  htrA Streptococcus mutans UA159

49.118

89.71

0.441

Multiple sequence alignment