Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SD311_RS09065 Genome accession   NZ_CP166245
Coordinates   1891828..1892457 (-) Length   209 a.a.
NCBI ID   WP_017723494.1    Uniprot ID   -
Organism   Staphylococcus sp. KG4-3     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1886828..1897457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD311_RS09035 (SD311_009035) - 1887094..1887615 (-) 522 WP_017723500.1 acyl-CoA thioesterase -
  SD311_RS09040 (SD311_009040) - 1887708..1888946 (-) 1239 WP_107551833.1 aminopeptidase -
  SD311_RS09045 (SD311_009045) - 1888964..1889167 (-) 204 WP_017723498.1 DUF1128 family protein -
  SD311_RS09050 (SD311_009050) - 1889302..1889766 (+) 465 WP_017723497.1 low molecular weight protein-tyrosine-phosphatase -
  SD311_RS09055 (SD311_009055) - 1889773..1890057 (+) 285 WP_017723496.1 hypothetical protein -
  SD311_RS09060 (SD311_009060) - 1890413..1891558 (+) 1146 WP_017723495.1 YihY/virulence factor BrkB family protein -
  SD311_RS09065 (SD311_009065) vraR 1891828..1892457 (-) 630 WP_017723494.1 response regulator transcription factor Regulator
  SD311_RS09070 (SD311_009070) vraS 1892447..1893490 (-) 1044 WP_017723493.1 sensor histidine kinase Regulator
  SD311_RS09075 (SD311_009075) liaF 1893487..1894188 (-) 702 WP_017723492.1 cell wall-active antibiotics response protein LiaF -
  SD311_RS09080 (SD311_009080) - 1894205..1894591 (-) 387 WP_017723491.1 hypothetical protein -
  SD311_RS09085 (SD311_009085) map 1894696..1895448 (-) 753 WP_017723490.1 type I methionyl aminopeptidase -
  SD311_RS09090 (SD311_009090) - 1895625..1896611 (+) 987 WP_017723489.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23734.27 Da        Isoelectric Point: 4.7778

>NTDB_id=1033964 SD311_RS09065 WP_017723494.1 1891828..1892457(-) (vraR) [Staphylococcus sp. KG4-3]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGKEAIEKAHQLNPDLILMDLLMDDMDGVEATEQVKKDLPHMKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1033964 SD311_RS09065 WP_017723494.1 1891828..1892457(-) (vraR) [Staphylococcus sp. KG4-3]
ATGCCGATTAAAGTTTTATTTGTGGATGACCATGAAATGGTCCGAATTGGAATATCTAGCTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGGAAATCCGGAAAGGAAGCAATTGAAAAGGCACACCAATTGAATCCAGATTTAATATTAA
TGGATTTACTAATGGATGATATGGACGGTGTTGAAGCAACTGAACAAGTTAAAAAAGATTTACCTCATATGAAGGTAGTC
ATGCTTACGAGTTATATAGAAGATAACGAAGTATACCGTGCGCTTGATTCTGGTGTAGATAGTTACATTTTAAAAACAAC
GAGCGCTAGTGATATTGCAGAAGCAATAAGAAAAACCTATAATAATGAATCGGTTTTTGAAGCAGAAGTTTTAGTTAAGA
TGAGAAATAGGATGAAACAACGTGCAGAATTATATGAAATGTTAACAGAGCGTGAGATGGAAATCTTATTATTAATTGCA
AAAGGCTACTCAAACCAAGAAATAGCAAGCGCCTCACATATTACAATTAAAACCGTTAAAACACATGTAAGTAATATTTT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCTGTTATTTACGCTTTTCAACACAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment