Detailed information NTG1033965

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SD311_RS09070
• Genome accession: NZ_CP166245
• Coordinates: 1892447..1893490 (-)
• Length: 347 a.a.
• NCBI ID: WP_017723493.1
• Uniprot ID: A0A418IPK4
• Organism: Staphylococcus sp. KG4-3
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1887447..1898490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SD311_RS09040 (SD311_009040)	-	1887708..1888946 (-)	1239	WP_107551833.1	aminopeptidase	-
SD311_RS09045 (SD311_009045)	-	1888964..1889167 (-)	204	WP_017723498.1	DUF1128 family protein	-
SD311_RS09050 (SD311_009050)	-	1889302..1889766 (+)	465	WP_017723497.1	low molecular weight protein-tyrosine-phosphatase	-
SD311_RS09055 (SD311_009055)	-	1889773..1890057 (+)	285	WP_017723496.1	hypothetical protein	-
SD311_RS09060 (SD311_009060)	-	1890413..1891558 (+)	1146	WP_017723495.1	YihY/virulence factor BrkB family protein	-
SD311_RS09065 (SD311_009065)	vraR	1891828..1892457 (-)	630	WP_017723494.1	response regulator transcription factor	Regulator
SD311_RS09070 (SD311_009070)	vraS	1892447..1893490 (-)	1044	WP_017723493.1	sensor histidine kinase	Regulator
SD311_RS09075 (SD311_009075)	liaF	1893487..1894188 (-)	702	WP_017723492.1	cell wall-active antibiotics response protein LiaF	-
SD311_RS09080 (SD311_009080)	-	1894205..1894591 (-)	387	WP_017723491.1	hypothetical protein	-
SD311_RS09085 (SD311_009085)	map	1894696..1895448 (-)	753	WP_017723490.1	type I methionyl aminopeptidase	-
SD311_RS09090 (SD311_009090)	-	1895625..1896611 (+)	987	WP_017723489.1	aromatic acid exporter family protein	-
SD311_RS09095 (SD311_009095)	-	1896804..1897526 (-)	723	WP_017723488.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40051.58 Da
• Isoelectric Point: 6.4215

>NTDB_id=1033965 SD311_RS09070 WP_017723493.1 1892447..1893490(-) (vraS) [Staphylococcus sp. KG4-3]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=1033965 SD311_RS09070 WP_017723493.1 1892447..1893490(-) (vraS) [Staphylococcus sp. KG4-3]
ATGAATCACTATATTAGAGCAATAGGTTCAATGTTGATATTAGTTTATAGTACATTTTTTGCCATATTTTTTATTGATAA
AGTATTTGTTAACATCATGTACTTTCAAGGTATGTTTTATACGCAAATATTTGGTATACCCGTCTTATTATTTTTAAATC
TAATGGTTATTTTACTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAGCAAAACCATTGGTTAAAAGAC
CAAATAGAAAGGTCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACAAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGTTAGCACGCGAACTACATGATTCGGTGAGT
CAACAGTTGTTCGCAGCTAGCATGATGTTATCAGCGATAAAAGAAACAAAATTAGAAGCACCATTAGATCAACAAATTCC
AGTACTAGAAAAAATGATACAAGATTCTCAGCTAGAGATGAGAGCTTTATTATTACATTTAAGACCTTTAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGATTTGGTTGTAGATTTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATCGAAGATCATTTGTTTAGAATCACACAAGAAGCTATATCGAATACGTTAAGGCA
TTCGAAAGGAACTAAAGTGACTATAGAGTTATTCAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTAGATGATAAAGTAGAACAAAGTTATGGCTTGAAAAATATGCGTGAACGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCATTACCTGACGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A418IPK4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	89.049	100	0.89