Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AB6N81_RS00325 Genome accession   NZ_CP163559
Coordinates   31367..32083 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain B273     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 26367..37083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6N81_RS00310 (AB6N81_00310) - 27648..28601 (+) 954 WP_162160123.1 LacI family DNA-binding transcriptional regulator -
  AB6N81_RS00315 (AB6N81_00315) - 28861..30333 (+) 1473 WP_203162595.1 sucrose-6-phosphate hydrolase -
  AB6N81_RS00320 (AB6N81_00320) - 30340..31299 (+) 960 WP_369352043.1 carbohydrate kinase -
  AB6N81_RS00325 (AB6N81_00325) agrA 31367..32083 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  AB6N81_RS00330 (AB6N81_00330) agrC 32100..33389 (-) 1290 WP_203162596.1 quorum-sensing sensor histidine kinase AgrC -
  AB6N81_RS00335 (AB6N81_00335) agrD 33414..33554 (-) 141 WP_002487333.1 cyclic lactone autoinducer peptide AgrD -
  AB6N81_RS00340 (AB6N81_00340) - 33560..34123 (-) 564 WP_203162597.1 accessory gene regulator AgrB -
  AB6N81_RS00345 (AB6N81_00345) hld 34440..34517 (+) 78 WP_002494082.1 delta-hemolysin -
  AB6N81_RS00350 (AB6N81_00350) - 34889..35674 (-) 786 WP_002490351.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=1030558 AB6N81_RS00325 WP_002447515.1 31367..32083(-) (agrA) [Staphylococcus epidermidis strain B273]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1030558 AB6N81_RS00325 WP_002447515.1 31367..32083(-) (agrA) [Staphylococcus epidermidis strain B273]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCTTCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAACTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment