Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   AB6M99_RS04540 Genome accession   NZ_CP163513
Coordinates   955960..957330 (+) Length   456 a.a.
NCBI ID   WP_121834410.1    Uniprot ID   -
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 950960..962330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS04530 (AB6M99_04530) - 952682..954430 (+) 1749 WP_369351136.1 ABC transporter ATP-binding protein -
  AB6M99_RS04535 (AB6M99_04535) vicR 955257..955967 (+) 711 WP_369351137.1 response regulator YycF Regulator
  AB6M99_RS04540 (AB6M99_04540) vicK 955960..957330 (+) 1371 WP_121834410.1 cell wall metabolism sensor histidine kinase VicK Regulator
  AB6M99_RS04545 (AB6M99_04545) vicX 957311..958114 (+) 804 WP_245962669.1 MBL fold metallo-hydrolase Regulator
  AB6M99_RS04550 (AB6M99_04550) xseA 958385..959713 (+) 1329 WP_121834411.1 exodeoxyribonuclease VII large subunit -
  AB6M99_RS04555 (AB6M99_04555) - 959706..960185 (+) 480 WP_183121631.1 GNAT family N-acetyltransferase -
  AB6M99_RS04560 (AB6M99_04560) - 960333..960551 (+) 219 WP_121834413.1 exodeoxyribonuclease VII small subunit -
  AB6M99_RS04565 (AB6M99_04565) - 960551..961420 (+) 870 WP_121834414.1 polyprenyl synthetase family protein -
  AB6M99_RS04570 (AB6M99_04570) - 961413..962234 (+) 822 WP_121834415.1 TlyA family RNA methyltransferase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51599.52 Da        Isoelectric Point: 4.6100

>NTDB_id=1030291 AB6M99_RS04540 WP_121834410.1 955960..957330(+) (vicK) [Streptococcus hillyeri strain S23-3001-2]
MTNLTDNLGIFESFLLLLLGITATYLLYGAYRDYRQAKIIRQLTENVYALIDGEYSDILDVAADSDLEDLANSLSDLSEV
VRLTHGNLSQERDRLSSLLAYMTDGVLATDRGGKIVTINETAQKQLNLTAEQALKMTILDILGSDNPYSYHDLVVKTPNI
LINRRNEFGEFMTLRFRFALNRRESGFISGLVVVLHDVTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKD
DVAPQFIKVSLDETNRMMRMITDLLNLSRIDNGAVQLEVEMTNFTAFMTSILNRFDKVKSQHTTSDKNFEIVRDYPLTSV
WMEIDNDKMTQVIENILNNAIKYSPDGGQIKVSMKTTDSQLIVSITDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHQGFIWAKSEEGKGSTFTIVLPYDKEVLELDEWEDYEDNGDGKGV

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=1030291 AB6M99_RS04540 WP_121834410.1 955960..957330(+) (vicK) [Streptococcus hillyeri strain S23-3001-2]
ATGACTAATTTAACAGATAATTTAGGAATTTTTGAGAGTTTTCTTTTACTCCTTTTGGGAATAACGGCGACATATCTCTT
GTACGGTGCCTATCGTGATTATAGGCAGGCAAAGATTATTCGTCAGTTGACTGAAAATGTTTACGCCCTGATTGATGGGG
AGTATTCAGATATTTTGGACGTTGCAGCTGATTCGGATTTAGAAGATCTTGCCAATAGTCTCAGTGATTTGTCTGAGGTG
GTTCGCTTGACTCACGGTAATTTATCACAGGAAAGAGACCGTCTTTCTAGCCTTTTAGCTTATATGACTGATGGGGTTTT
AGCGACTGACCGTGGTGGTAAAATTGTCACGATTAATGAAACTGCTCAAAAACAGCTTAATTTAACTGCTGAGCAAGCCT
TGAAGATGACCATCCTAGATATTCTTGGGAGTGATAATCCTTATTCTTACCATGATTTGGTTGTTAAAACACCGAATATT
TTGATTAATCGCCGAAATGAATTTGGGGAATTCATGACGTTACGTTTTCGTTTTGCCTTAAACCGTCGAGAGTCTGGTTT
TATTTCGGGATTAGTTGTGGTGTTGCACGATGTTACAGAACAAGAAAAAGAAGAGCGTGAACGTCGTCTTTTTGTATCAA
ATGTTAGTCACGAGTTGCGCACGCCATTAACTTCGGTAAAATCGTATTTAGAGGCTCTTGATGAAGGGGCTCTAAAAGAT
GATGTTGCTCCGCAATTTATCAAAGTATCCTTAGACGAGACTAACCGTATGATGCGTATGATTACTGACCTTCTTAACCT
TTCTAGAATTGATAATGGTGCGGTGCAGTTAGAAGTAGAAATGACAAATTTTACAGCTTTTATGACGTCAATTTTGAATC
GCTTTGATAAAGTTAAAAGTCAGCATACAACATCTGATAAGAATTTTGAGATTGTTCGTGACTATCCCTTGACATCTGTT
TGGATGGAGATTGATAATGACAAAATGACACAGGTTATTGAAAATATTTTAAATAATGCAATCAAGTATTCACCTGATGG
TGGGCAGATTAAGGTGAGTATGAAAACCACGGATAGTCAGTTAATTGTTTCTATTACAGACCAAGGATTAGGCATTCCTA
AAAAGGATTTGCCGTTGATTTTTGACCGCTTTTATCGCGTTGATAAAGCCAGAAGTCGTGCTCAAGGTGGAACAGGTTTA
GGTCTATCAATTGCTAAAGAAATTGTGAAACAACACCAAGGTTTCATTTGGGCTAAAAGTGAGGAAGGTAAGGGGTCAAC
CTTTACAATTGTTTTGCCTTATGACAAAGAAGTTCTAGAATTGGATGAATGGGAGGATTACGAAGACAATGGTGATGGAA
AAGGGGTTTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-180)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

71.913

90.57

0.651
  micB Streptococcus pneumoniae Cp1015

66.2

94.079

0.623

Multiple sequence alignment