Detailed information NTG1027894

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: C7S02_RS11285
• Genome accession: NZ_LT591908
• Coordinates: 1886789..1888015 (-)
• Length: 408 a.a.
• NCBI ID: WP_047926530.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO K
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1881789..1893015

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7S02_RS11270 (WHOK_02072)	-	1883759..1884043 (+)	285	WP_003692093.1	GIY-YIG nuclease family protein	-
C7S02_RS11280 (WHOK_02073C)	yccS	1884522..1886672 (-)	2151	WP_003699137.1	YccS family putative transporter	-
C7S02_RS11285 (WHOK_02074C)	pilU	1886789..1888015 (-)	1227	WP_047926530.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
C7S02_RS11290 (WHOK_02075C)	pilT	1888179..1889222 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
C7S02_RS11295 (WHOK_02076)	-	1889342..1890028 (+)	687	WP_003690201.1	YggS family pyridoxal phosphate-dependent enzyme	-
C7S02_RS11300 (WHOK_02077)	-	1890028..1890435 (+)	408	WP_003701818.1	hypothetical protein	-
C7S02_RS11305 (WHOK_02078)	proC	1890466..1891275 (+)	810	WP_228547131.1	pyrroline-5-carboxylate reductase	-
C7S02_RS11310 (WHOK_02079)	dksA	1891424..1891840 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45596.24 Da
• Isoelectric Point: 7.5293

>NTDB_id=1027894 C7S02_RS11285 WP_047926530.1 1886789..1888015(-) (pilU) [Neisseria gonorrhoeae strain WHO K]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYYSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGG
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=1027894 C7S02_RS11285 WP_047926530.1 1886789..1888015(-) (pilU) [Neisseria gonorrhoeae strain WHO K]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACTACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGGA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.598	88.48	0.395
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	46.45	82.843	0.385