Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQL18_RS04020 Genome accession   NZ_LS483486
Coordinates   763848..765068 (+) Length   406 a.a.
NCBI ID   WP_042601844.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12194     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 758848..770068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL18_RS04000 (NCTC12194_00808) corC 759815..760714 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  DQL18_RS04005 (NCTC12194_00809) ampD 761336..761896 (-) 561 WP_011271974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQL18_RS04010 (NCTC12194_00810) pilA 762011..762460 (+) 450 WP_011271973.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQL18_RS04015 (NCTC12194_00811) pilB 762457..763851 (+) 1395 WP_105905461.1 GspE/PulE family protein Machinery gene
  DQL18_RS04020 (NCTC12194_00812) pilC 763848..765068 (+) 1221 WP_042601844.1 type II secretion system F family protein Machinery gene
  DQL18_RS04025 (NCTC12194_00813) pilD 765065..765757 (+) 693 WP_105905460.1 prepilin peptidase Machinery gene
  DQL18_RS04030 (NCTC12194_00814) rho 765811..767073 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  DQL18_RS04035 (NCTC12194_00815) metJ 767321..767638 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DQL18_RS04040 (NCTC12194_00816) cueR 767652..768038 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQL18_RS04045 (NCTC12194_00817) - 768115..768321 (+) 207 WP_048941374.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04050 (NCTC12194_00818) - 768395..768601 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04055 (NCTC12194_00819) - 768675..768881 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04060 (NCTC12194_00820) - 768955..769161 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04065 (NCTC12194_00821) - 769235..769441 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04070 (NCTC12194_00822) - 769515..769721 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04075 (NCTC12194_00823) - 769807..770013 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46205.41 Da        Isoelectric Point: 9.7152

>NTDB_id=1025941 DQL18_RS04020 WP_042601844.1 763848..765068(+) (pilC) [Haemophilus influenzae strain NCTC12194]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQDCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1025941 DQL18_RS04020 WP_042601844.1 763848..765068(+) (pilC) [Haemophilus influenzae strain NCTC12194]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAGATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.98
  pilC Haemophilus influenzae Rd KW20

97.291

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment