Detailed information NTG1024917

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: AB3W22_RS24455
• Genome accession: NZ_CP162335
• Coordinates: 5242024..5243361 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 1001d0_1
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5237024..5248361

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3W22_RS24430 (AB3W22_24430)	pgeF	5237167..5237895 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
AB3W22_RS24435 (AB3W22_24435)	rluD	5237892..5238854 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
AB3W22_RS24440 (AB3W22_24440)	-	5239000..5240025 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
AB3W22_RS24445 (AB3W22_24445)	-	5240182..5240427 (+)	246	WP_003102591.1	PP0621 family protein	-
AB3W22_RS24450 (AB3W22_24450)	pilS	5240417..5242009 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
AB3W22_RS24455 (AB3W22_24455)	pilR	5242024..5243361 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
AB3W22_RS24460 (AB3W22_24460)	thiO	5243407..5244501 (-)	1095	WP_023122775.1	glycine oxidase ThiO	-
AB3W22_RS24465 (AB3W22_24465)	-	5244641..5245141 (+)	501	WP_016562346.1	GspH/FimT family pseudopilin	-
AB3W22_RS24470 (AB3W22_24470)	-	5245264..5245752 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
AB3W22_RS24475 (AB3W22_24475)	pilV	5245762..5246286 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
AB3W22_RS24480 (AB3W22_24480)	-	5246295..5247110 (+)	816	WP_016562347.1	PilW family protein	-
AB3W22_RS24485 (AB3W22_24485)	-	5247107..5247712 (+)	606	WP_003116263.1	PilX N-terminal domain-containing pilus assembly protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1024917 AB3W22_RS24455 WP_003094694.1 5242024..5243361(+) (pilR) [Pseudomonas aeruginosa strain 1001d0_1]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1024917 AB3W22_RS24455 WP_003094694.1 5242024..5243361(+) (pilR) [Pseudomonas aeruginosa strain 1001d0_1]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384