Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ABW635_RS04540 Genome accession   NZ_CP162310
Coordinates   927841..929151 (+) Length   436 a.a.
NCBI ID   WP_003099509.1    Uniprot ID   A0A3L8GJR1
Organism   Streptococcus iniae strain ZQ2205     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 922841..934151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABW635_RS04520 (ABW635_04520) pstB 922988..923746 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  ABW635_RS04525 (ABW635_04525) phoU 923801..924454 (+) 654 WP_003099503.1 phosphate signaling complex protein PhoU -
  ABW635_RS04530 (ABW635_04530) - 924516..927053 (+) 2538 WP_003099506.1 M1 family metallopeptidase -
  ABW635_RS04535 (ABW635_04535) ciaR 927174..927848 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  ABW635_RS04540 (ABW635_04540) ciaH 927841..929151 (+) 1311 WP_003099509.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ABW635_RS04545 (ABW635_04545) rpsT 929323..929565 (-) 243 WP_080613191.1 30S ribosomal protein S20 -
  ABW635_RS04550 (ABW635_04550) coaA 929625..930545 (-) 921 WP_003099512.1 type I pantothenate kinase -
  ABW635_RS04555 (ABW635_04555) - 930806..931405 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -
  ABW635_RS04560 (ABW635_04560) - 931392..932669 (+) 1278 WP_003099515.1 pyrimidine-nucleoside phosphorylase -
  ABW635_RS04565 (ABW635_04565) deoC 932681..933343 (+) 663 WP_003099517.1 deoxyribose-phosphate aldolase -
  ABW635_RS04570 (ABW635_04570) - 933315..933719 (+) 405 WP_230453495.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49969.52 Da        Isoelectric Point: 9.1099

>NTDB_id=1024859 ABW635_RS04540 WP_003099509.1 927841..929151(+) (ciaH) [Streptococcus iniae strain ZQ2205]
MANLKRIYQSDNFGHFFHFFAVFTGIFVVMTMIIIQIMQYGVYSSVDSSLLAVSKNSSVYANLTMERMTSFYFDNQEDAF
KNGTEVFKAALVEQPVANTDIILFSSNGTVLNSFDALSGFQNFTLKTNELNAIRTRKLMNFYGHEEKYHTLTVKIHSNRY
PAVAYLMAVVNVEQLDRANERYERIIVLVMITFWFISVLASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNETILENSEPIASSLEEVRNMKILTTNLLNLARRDDGINPELVDVDASFFDAMFENFNLVAEDYGKDFHFEN
QVKRTIKMDKSLLKQLITILFDNALKYTDSDGQISISVRTTDKNLMVRVLDDGPGIKDMDKKKVFDRFYRVDKARTRTKG
GFGLGLSLAKQIVASLNGTISVKDNKPKGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1024859 ABW635_RS04540 WP_003099509.1 927841..929151(+) (ciaH) [Streptococcus iniae strain ZQ2205]
ATGGCTAATTTAAAACGTATTTACCAGTCAGATAATTTTGGGCATTTTTTCCATTTTTTTGCAGTCTTTACAGGAATATT
TGTTGTCATGACCATGATTATCATTCAAATCATGCAGTACGGTGTTTATTCTTCGGTAGATAGTAGTCTACTTGCTGTGT
CAAAAAATTCATCGGTTTATGCTAATTTAACCATGGAACGAATGACCTCATTTTACTTTGATAATCAAGAGGATGCTTTT
AAAAATGGAACTGAAGTCTTTAAAGCAGCCTTAGTTGAACAACCAGTTGCCAATACGGATATTATCCTCTTTAGTTCTAA
CGGAACGGTTTTAAATAGCTTTGATGCGCTATCGGGTTTTCAAAATTTTACCTTAAAAACAAATGAATTAAATGCCATTC
GAACACGGAAATTGATGAATTTTTACGGGCATGAAGAAAAATACCATACGCTGACAGTTAAGATTCATTCCAATAGGTAC
CCAGCGGTGGCTTACCTAATGGCAGTTGTCAATGTGGAACAATTGGACCGTGCCAATGAGCGCTATGAACGAATCATTGT
TCTTGTTATGATAACTTTCTGGTTTATTTCTGTTTTGGCCAGTATATACCTTGCAAAATGGAGTCGTAAACCAATTCTTG
AAAGTTATGAGAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGAACTCCCTTAGCAGTATTACAAAATCGC
TTAGAGACCCTGTTTAGAAAACCTAATGAAACAATTCTGGAAAACAGTGAACCAATTGCTTCGAGTTTAGAAGAAGTGCG
CAATATGAAGATCTTAACCACAAATTTATTGAATCTTGCCAGACGCGATGATGGGATTAATCCAGAACTCGTTGATGTGG
ATGCAAGCTTTTTTGACGCTATGTTTGAAAACTTCAACTTAGTAGCTGAAGATTATGGTAAAGACTTCCATTTTGAAAAT
CAGGTTAAGCGGACAATAAAAATGGATAAATCTTTATTAAAACAATTGATTACCATTTTATTTGATAATGCTTTGAAATA
CACGGACTCTGATGGGCAAATTTCAATTAGTGTTCGAACAACAGATAAAAATTTAATGGTCAGAGTGCTAGATGATGGTC
CTGGAATAAAAGACATGGATAAAAAGAAAGTTTTTGACCGCTTCTATCGTGTTGATAAGGCTAGAACACGTACTAAAGGT
GGATTTGGTTTGGGACTTTCTTTAGCAAAACAGATTGTTGCTTCCTTAAATGGAACAATATCAGTTAAAGACAATAAACC
AAAAGGGACAATATTTGAAGTTAAACTCTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GJR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.275

99.312

0.569
  ciaH Streptococcus pneumoniae Rx1

51.835

100

0.518
  ciaH Streptococcus pneumoniae D39

51.835

100

0.518
  ciaH Streptococcus pneumoniae R6

51.835

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.835

100

0.518

Multiple sequence alignment