Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AI22_RS00625 Genome accession   NZ_CP007147
Coordinates   130096..130740 (+) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa YL84     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 125096..135740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AI22_RS00600 (AI22_00595) - 125588..127069 (-) 1482 WP_003101642.1 AAA family ATPase -
  AI22_RS00605 (AI22_00600) - 127148..127486 (+) 339 WP_003085225.1 histidine triad nucleotide-binding protein -
  AI22_RS00610 (AI22_00605) coq7 127586..128233 (+) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  AI22_RS00615 (AI22_00610) speD 128288..129082 (-) 795 WP_003101641.1 adenosylmethionine decarboxylase -
  AI22_RS00620 (AI22_00615) - 129402..129824 (-) 423 WP_003085219.1 OsmC family protein -
  AI22_RS00625 (AI22_00620) crp 130096..130740 (+) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  AI22_RS00630 (AI22_00625) trpC 130802..131638 (-) 837 WP_003085205.1 indole-3-glycerol phosphate synthase TrpC -
  AI22_RS00635 (AI22_00630) trpD 131635..132684 (-) 1050 WP_016252940.1 anthranilate phosphoribosyltransferase -
  AI22_RS00640 (AI22_00635) - 132686..133291 (-) 606 WP_003101640.1 aminodeoxychorismate/anthranilate synthase component II -
  AI22_RS00645 (AI22_00640) - 133697..133924 (-) 228 WP_016252939.1 hypothetical protein -
  AI22_RS00650 (AI22_00645) - 133921..134232 (-) 312 WP_025324545.1 hypothetical protein -
  AI22_RS00655 (AI22_00650) - 134232..135332 (-) 1101 WP_016252938.1 pyocin knob domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=102484 AI22_RS00625 WP_003085214.1 130096..130740(+) (crp) [Pseudomonas aeruginosa YL84]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=102484 AI22_RS00625 WP_003085214.1 130096..130740(+) (crp) [Pseudomonas aeruginosa YL84]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGCGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGAAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505

Multiple sequence alignment