Detailed information NTG1024771

Bioinformatically predicted

Overview

• Name: comD/blpH
• Type: Regulator
• Locus tag: DQN42_RS09800
• Genome accession: NZ_LS483436
• Coordinates: 563617..564438 (-)
• Length: 273 a.a.
• NCBI ID: WP_231840239.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain NCTC11324
• Function: phosphorylation of ComE; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 558617..569438

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN42_RS02850 (NCTC11324_00580)	-	558911..559285 (-)	375	WP_003073369.1	hypothetical protein	-
DQN42_RS02860 (NCTC11324_00582)	comA/nlmT	559766..561916 (+)	2151	WP_004234001.1	peptide cleavage/export ABC transporter	Regulator
DQN42_RS02865 (NCTC11324_00583)	-	561927..563288 (+)	1362	WP_003078103.1	bacteriocin secretion accessory protein	-
DQN42_RS02870	-	563402..563536 (+)	135	WP_004233948.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQN42_RS09800	comD/blpH	563617..564438 (-)	822	WP_231840239.1	sensor histidine kinase	Regulator
DQN42_RS02880 (NCTC11324_00585)	comE/blpR	564935..565681 (-)	747	WP_037589556.1	response regulator transcription factor	Regulator
DQN42_RS02885 (NCTC11324_00586)	-	565850..566563 (-)	714	WP_004233848.1	CPBP family intramembrane glutamic endopeptidase	-
DQN42_RS02890 (NCTC11324_00587)	-	566795..567022 (+)	228	WP_004233901.1	bacteriocin	-
DQN42_RS02895 (NCTC11324_00588)	-	567058..567378 (+)	321	WP_003073339.1	hypothetical protein	-
DQN42_RS02900 (NCTC11324_00589)	-	567608..567823 (+)	216	WP_004233876.1	bacteriocin class II family protein	-
DQN42_RS02905 (NCTC11324_00590)	-	568051..568344 (+)	294	WP_004233800.1	bacteriocin immunity protein	-
DQN42_RS02910 (NCTC11324_00591)	-	568438..568662 (+)	225	WP_004234003.1	Blp family class II bacteriocin	-
DQN42_RS09660 (NCTC11324_00593)	-	569078..569224 (+)	147	WP_004233732.1	hypothetical protein	-

Sequence

Protein

• Length: 273 a.a.
• Molecular weight: 31185.02 Da
• Isoelectric Point: 6.4236

>NTDB_id=1024771 DQN42_RS09800 WP_231840239.1 563617..564438(-) (comD/blpH) [Streptococcus intermedius strain NCTC11324]
MVLYYIILQLLAYIEYTKFTTTLFVREALVIIYLVFFLIITNRLDLHLRERIQNDLMLQKDLQLKNLENYSHHIEELYTE
VRSFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIGRLVHIKNDALKSLLAAKFAQAQEHNVSVSL
EVPEDICPQGMELVDFITIVSILCDNAIEAAAPTMTIAYVLSGNKQVFSIENAIKEEHIDMSYIFDAGVSSKGSGRGIGL
SNVLAILDRYPNVSLASTSQNHCFQHILEIHLN

Nucleotide

• Length: 822 bp

>NTDB_id=1024771 DQN42_RS09800 WP_231840239.1 563617..564438(-) (comD/blpH) [Streptococcus intermedius strain NCTC11324]
ATGGTATTGTACTATATCATTCTCCAACTATTGGCGTATATAGAATACACTAAATTTACAACAACTCTTTTTGTTAGAGA
AGCATTGGTTATTATTTATCTAGTATTCTTTTTGATTATTACTAACCGACTGGACCTTCATTTACGGGAGAGAATCCAAA
ATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAACTTGGAAAACTACAGTCATCACATTGAAGAATTGTACACAGAA
GTTCGGAGCTTTCGGCATGATTACGCAAATATTTTAACAACCTTGAAATTAGGAATTGAGCAAAATGATATAGGCATTGT
AAAGAATGTTTATCATTCTGTTTTGAAAGATTCCAATAAGCGTTTTCGCAATCCCAAGTATGATATTGGACGGTTAGTCC
ATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTATCCGTTTCATTG
GAAGTTCCAGAAGATATTTGTCCACAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCCATTTTGTGTGATAATGC
GATTGAAGCTGCTGCTCCAACTATGACGATTGCTTATGTTTTGTCAGGAAACAAGCAGGTATTCTCCATTGAAAATGCTA
TAAAAGAAGAGCATATAGACATGTCTTATATTTTTGATGCGGGAGTTAGTTCTAAAGGATCTGGGCGAGGAATTGGATTA
TCAAATGTCTTAGCAATTCTGGATCGATATCCAAATGTTTCACTTGCTAGTACTAGCCAGAATCACTGCTTTCAGCACAT
CCTTGAGATTCATCTGAATTAG

Domains

Predicted by InterProScan.

• GHKL domain (HATPase_c_5) (171-268)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/blpH	Streptococcus mutans UA159	44.526	100	0.447
comD/comD3	Streptococcus equinus JB1	39.442	91.941	0.363