Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DQN42_RS02185 Genome accession   NZ_LS483436
Coordinates   432594..433226 (+) Length   210 a.a.
NCBI ID   WP_003078408.1    Uniprot ID   -
Organism   Streptococcus intermedius strain NCTC11324     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 427594..438226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN42_RS02165 (NCTC11324_00439) - 428028..428768 (+) 741 WP_003073671.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQN42_RS02170 (NCTC11324_00440) stkP 428765..430639 (+) 1875 WP_003073669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQN42_RS02175 (NCTC11324_00441) liaF 430902..431600 (+) 699 WP_003078234.1 cell wall-active antibiotics response protein LiaF -
  DQN42_RS02180 (NCTC11324_00442) - 431597..432592 (+) 996 WP_003078340.1 sensor histidine kinase -
  DQN42_RS02185 (NCTC11324_00443) vraR 432594..433226 (+) 633 WP_003078408.1 response regulator transcription factor Regulator
  DQN42_RS02190 (NCTC11324_00444) - 433266..434666 (+) 1401 WP_003078255.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQN42_RS02195 (NCTC11324_00445) - 434668..435060 (+) 393 WP_014829583.1 S1 RNA-binding domain-containing protein -
  DQN42_RS02200 (NCTC11324_00446) - 435180..435497 (-) 318 WP_003073656.1 DUF960 domain-containing protein -
  DQN42_RS02205 (NCTC11324_00447) - 435617..436150 (-) 534 WP_003073655.1 DUF402 domain-containing protein -
  DQN42_RS02210 (NCTC11324_00448) recX 436237..437013 (-) 777 WP_003078225.1 recombination regulator RecX -
  DQN42_RS02215 (NCTC11324_00449) - 437077..437853 (-) 777 WP_003078296.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23711.38 Da        Isoelectric Point: 4.7982

>NTDB_id=1024682 DQN42_RS02185 WP_003078408.1 432594..433226(+) (vraR) [Streptococcus intermedius strain NCTC11324]
MQILLVDDHEMVRLGLKSYLDVQDDVDMVVEASNGCEGVEKALSLRPDVIMMDIVMPKMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEELTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1024682 DQN42_RS02185 WP_003078408.1 432594..433226(+) (vraR) [Streptococcus intermedius strain NCTC11324]
ATGCAGATTTTATTAGTAGATGATCATGAAATGGTGCGACTTGGTTTGAAGAGCTATTTGGATGTACAAGATGATGTTGA
TATGGTGGTAGAAGCTTCAAATGGTTGTGAAGGGGTGGAAAAGGCTCTGTCATTACGACCAGATGTGATAATGATGGATA
TTGTCATGCCTAAAATGAATGGGATTGAAGCTACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTTATTTTG
ACTTCTTATTTAGATAATGAAAAAATTTACCCAGTTTTAGATGCAGGGGCTAAAGGGTACATGCTTAAAACATCTAGTGC
TGACGATATCTTACGAGCAGTTCGAAAGGTAGCCAAGGGTGAACTTGCTATTGAAACGGAGGTCAGTCAGAAAGTGGAAT
ACCATCGAAATCATATTGAATTACATGAAGAGCTAACAGCGCGTGAGCGCGATATTTTAGGTCTATTAGCAAAAGGGTAT
GAAAATCAACGGATAGCAGATGAGTTGTTTATTTCGTTGAAGACTGTTAAAACACATGTATCTAATATCTTATCAAAATT
AGAAGTAAGTGATCGGACACAAGCTGTTGTTTACGCCTTTCAGCACCACCTTGTCCCACAAGATGACATTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414