Detailed information NTG1024006

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: DQM62_RS01235
• Genome accession: NZ_LS483418
• Coordinates: 220899..223232 (+)
• Length: 777 a.a.
• NCBI ID: WP_012775425.1
• Uniprot ID: A0A0H3MT16
• Organism: Streptococcus suis strain NCTC10234
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 215899..228232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM62_RS09955	-	215995..216156 (-)	162	Protein_191	PTS beta-glucoside transporter subunit IIBCA	-
DQM62_RS01210	-	216203..217050 (+)	848	WP_111688386.1	IS630 family transposase	-
DQM62_RS01215 (NCTC10234_00235)	treP	217055..218887 (-)	1833	Protein_193	PTS system trehalose-specific EIIBC component	-
DQM62_RS01220 (NCTC10234_00236)	treR	219121..219834 (+)	714	WP_012774930.1	trehalose operon repressor	Regulator
DQM62_RS01225 (NCTC10234_00237)	-	219892..220203 (+)	312	WP_002935948.1	hypothetical protein	-
DQM62_RS01230 (NCTC10234_00238)	-	220200..220748 (+)	549	WP_002935945.1	CvpA family protein	-
DQM62_RS01235 (NCTC10234_00239)	mutS/mutS2	220899..223232 (+)	2334	WP_012775425.1	endonuclease MutS2	Machinery gene
DQM62_RS01240 (NCTC10234_00240)	-	223256..223909 (+)	654	WP_011921818.1	GNAT family N-acetyltransferase	-
DQM62_RS01245 (NCTC10234_00241)	trxA	224116..224430 (+)	315	WP_012775426.1	thioredoxin	-
DQM62_RS10185	-	224658..224708 (-)	51	WP_353735889.1	hypothetical protein	-
DQM62_RS01250 (NCTC10234_00242)	-	224698..226227 (+)	1530	WP_012774931.1	AMP-binding protein	-
DQM62_RS01255 (NCTC10234_00243)	msrB	226267..227205 (+)	939	WP_011921822.1	peptide-methionine (R)-S-oxide reductase MsrB	-
DQM62_RS01260 (NCTC10234_00244)	-	227323..228201 (+)	879	WP_014635840.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 777 a.a.
• Molecular weight: 87550.34 Da
• Isoelectric Point: 6.8323

>NTDB_id=1024006 DQM62_RS01235 WP_012775425.1 220899..223232(+) (mutS/mutS2) [Streptococcus suis strain NCTC10234]
MNNKIIETLEFHKVRQKIEPYLLTEQGFEELRQLEPMVEVHRIQQAFDELTDIAQIFVENPYFSLAATSDIGPAMRRLEL
DTDLNIAELLAVKKVLEVSKSLLDFYGNLENVSLSQLDKLFEKIELFPHLQGSLQSINDAGFVEDFASEKLARIRRKIRE
AEDQVRQVMQDILKTKGDMLSDSILASRNGRNVLPVKNTYRNKIAGVVHDISASGSTVYIEPRAVVTLNEEISHLRAEER
HELNRILQELSDMLRPHGGVIRNNAWLIGHIDFVRAKHLFARDHQAVVPKLSEKQDIALLNVRHPLIAKPVPNDLYFGSQ
LTAIVITGPNTGGKTIMLKTLGLTHLMAQSGLPILADKGSRVAIFKEIFADIGDEQSIEQSLSTFSSHMTHTVEILRAAD
QDSLILFDELGAGTDPQEGASLAMAILDDLRLRGIKTMATTHYPELKAYGIETSGIENASMEFDSNSLRPTYKFMQGVPG
RSNAFEIARRLGLSDIIIQSAQSWTDTDSDVNRIIEKLESQTVESRQRLDKIRDVEQENYKMNRALRKLYDELNRERENE
LNKARLEAKEIVDMALAESEDILKNLHAAASLKPHQIIEAKAELKKLAPEVVDLSKNKVLKKAKIKREAKVGDDIIVTAY
GQRGTLTNQLKDGRWEAQVGLIKMTLAKDEFELVKAEKAEQPKKRQVHTVKRANVRGPKARLDLRGKRYEEAMMELDEFI
DQALLNNLAQVDIVHGIGTGVIREGVTKYLRRNKQIKEFGYAPQNAGGSGCTIVTFK

Nucleotide

• Length: 2334 bp

>NTDB_id=1024006 DQM62_RS01235 WP_012775425.1 220899..223232(+) (mutS/mutS2) [Streptococcus suis strain NCTC10234]
ATGAATAATAAAATTATTGAAACCCTTGAATTTCACAAGGTAAGACAAAAAATTGAGCCCTATCTCTTGACGGAACAGGG
CTTTGAAGAATTACGACAGTTGGAGCCCATGGTGGAAGTCCATCGTATCCAACAGGCCTTCGACGAGTTGACAGACATAG
CGCAGATTTTTGTGGAAAATCCCTATTTCAGTCTGGCTGCTACTAGTGACATCGGTCCAGCCATGCGTCGTTTGGAATTG
GATACAGACCTCAATATCGCTGAATTATTAGCTGTTAAAAAGGTCTTGGAAGTTTCTAAATCTCTCTTGGATTTTTATGG
AAATCTGGAAAATGTCAGTCTTAGCCAGTTGGATAAACTCTTTGAGAAGATTGAGCTTTTTCCACATTTACAGGGCTCCC
TCCAGTCCATCAATGATGCTGGTTTTGTAGAGGATTTTGCCTCAGAAAAGCTGGCTCGTATTCGAAGAAAAATCCGTGAA
GCTGAAGATCAAGTTCGTCAGGTCATGCAGGATATTTTGAAGACCAAGGGCGACATGCTGTCCGATAGCATTTTGGCAAG
CCGTAATGGACGCAATGTCCTTCCTGTTAAAAATACCTATCGCAATAAGATTGCAGGGGTTGTCCATGACATTTCAGCTT
CGGGTTCGACCGTTTATATTGAGCCGCGGGCAGTGGTGACCTTGAACGAAGAAATCAGTCACCTACGTGCAGAAGAACGC
CATGAGCTCAACCGTATCTTGCAGGAATTGTCGGATATGCTCCGTCCGCATGGTGGCGTGATTCGTAACAATGCCTGGCT
TATCGGACATATTGATTTCGTCCGTGCTAAGCATCTCTTTGCGCGTGATCATCAAGCAGTTGTACCCAAACTATCTGAGA
AGCAGGATATTGCCCTTCTCAACGTTCGGCATCCGCTCATTGCTAAGCCTGTACCAAATGACCTTTATTTCGGTAGTCAG
TTGACGGCTATCGTGATAACAGGTCCCAACACAGGTGGTAAGACCATCATGCTTAAGACCTTGGGATTGACCCATCTGAT
GGCCCAGTCTGGTTTGCCTATCTTGGCTGATAAGGGCAGTCGGGTAGCTATCTTCAAAGAAATTTTTGCGGATATTGGGG
ATGAACAGTCGATTGAGCAGAGTTTATCAACCTTCTCCAGTCACATGACCCACACGGTGGAAATTTTAAGAGCAGCTGAT
CAAGATTCTCTCATTCTCTTTGACGAGTTGGGAGCTGGGACAGATCCGCAGGAGGGTGCGTCTTTGGCTATGGCTATTTT
GGATGACCTTCGTCTGCGGGGGATCAAGACCATGGCGACCACCCACTACCCTGAGCTTAAGGCCTACGGGATAGAAACCT
CTGGTATTGAAAATGCCAGCATGGAGTTTGATAGCAATAGCCTGCGTCCGACCTATAAGTTTATGCAGGGTGTTCCTGGT
CGCTCCAATGCCTTTGAAATTGCCCGCCGTCTTGGTCTATCTGATATTATTATCCAGTCAGCCCAATCTTGGACGGATAC
AGATAGCGATGTGAACCGCATTATCGAGAAATTGGAAAGTCAGACGGTTGAAAGTCGTCAACGTCTGGATAAGATTCGTG
ATGTGGAGCAAGAAAATTACAAGATGAACCGAGCCCTCCGCAAGCTCTATGACGAGCTCAATCGTGAGCGGGAAAATGAG
CTCAACAAGGCACGCTTGGAAGCCAAGGAAATTGTAGATATGGCATTGGCAGAAAGCGAGGATATTCTCAAAAATCTCCA
TGCTGCAGCTAGTCTTAAGCCCCATCAGATTATCGAAGCCAAGGCAGAGCTGAAAAAGTTGGCGCCTGAAGTGGTGGATC
TGTCTAAAAACAAGGTTCTGAAGAAAGCTAAAATTAAGAGGGAAGCCAAGGTGGGCGATGACATTATCGTTACAGCTTAT
GGACAACGCGGGACCTTGACCAATCAGCTCAAGGACGGGCGTTGGGAAGCTCAGGTTGGCTTGATTAAGATGACCTTGGC
TAAAGATGAGTTTGAGTTAGTCAAGGCGGAAAAGGCAGAGCAGCCTAAGAAACGCCAGGTTCACACAGTCAAACGTGCCA
ATGTACGAGGACCAAAAGCCCGCTTAGATCTCCGTGGCAAACGTTACGAAGAGGCTATGATGGAGCTGGATGAATTTATC
GACCAGGCCCTTCTCAATAACCTAGCCCAAGTCGATATTGTCCACGGTATTGGTACTGGAGTCATCCGAGAAGGGGTGAC
CAAGTACCTACGCCGCAACAAGCAGATCAAGGAGTTCGGCTATGCTCCACAAAATGCAGGTGGATCAGGCTGTACTATTG
TGACGTTTAAATAG

Domains

Predicted by InterProScan.

• MutS2 and Smr-associated SH3 domain (MSSS) (631-670)

• MutS domain V (MutS_V) (324-504)

• Smr domain (Smr) (702-777)

3D structure

• AlphaFold DB: A0A0H3MT16

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	39.52	100	0.403