Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQN23_RS04595 Genome accession   NZ_LS483403
Coordinates   896604..897932 (-) Length   442 a.a.
NCBI ID   WP_020916819.1    Uniprot ID   A0AB33ALY3
Organism   Streptococcus lutetiensis strain NCTC13774     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 891604..902932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN23_RS04570 (NCTC13774_00943) deoC 891945..892610 (-) 666 WP_111712815.1 deoxyribose-phosphate aldolase -
  DQN23_RS04575 (NCTC13774_00944) - 893113..893706 (-) 594 WP_061407804.1 class I SAM-dependent methyltransferase -
  DQN23_RS04580 (NCTC13774_00945) coaA 893838..894758 (+) 921 WP_020916817.1 type I pantothenate kinase -
  DQN23_RS04585 (NCTC13774_00946) rpsT 894834..895085 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  DQN23_RS04595 (NCTC13774_00949) ciaH 896604..897932 (-) 1329 WP_020916819.1 cell wall metabolism sensor histidine kinase WalK Regulator
  DQN23_RS04600 (NCTC13774_00950) ciaR 897922..898596 (-) 675 WP_020916820.1 response regulator transcription factor Regulator
  DQN23_RS04605 (NCTC13774_00951) - 898764..901307 (-) 2544 WP_111712817.1 M1 family metallopeptidase -
  DQN23_RS04610 (NCTC13774_00952) phoU 901538..902191 (-) 654 WP_020916822.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 50230.16 Da        Isoelectric Point: 6.5190

>NTDB_id=1023084 DQN23_RS04595 WP_020916819.1 896604..897932(-) (ciaH) [Streptococcus lutetiensis strain NCTC13774]
MLNNIHKKLSTGTFSNFFHFFIVFTGIFIIMTTIILQIMRYGLYSSVDTTLKNAADNASDYVTRTMERSDSIQSNNSFSN
SGKSKPSSNVASLSNVSVLLYDTNGKIVNAIDAFVQFGTLASSVDEDTIGEIKDEKMTTIFGQTEKYHVLTVRVYSSDYP
TIEYATFLISVSQLDEANERYVTITVSVMIIFWMISILASIYLANWMRKPILESYEKQKRFVENASHELRTPLAVLQNRL
ESLFRRPNATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIQPSIFNEIFENYNMIAEENGKTFVSHNF
ADRPIKTDRTLLKQLMTILFDNAIKYTDDDGFIEFTVKTTERQTILTVADNGPGISDADKAKIFDRFYRVDKARTRQKGG
FGLGLSLAKQIVDALKGDIQVKDNHPKGTIFEVRFNRYNFGK

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=1023084 DQN23_RS04595 WP_020916819.1 896604..897932(-) (ciaH) [Streptococcus lutetiensis strain NCTC13774]
ATGCTGAATAACATACACAAAAAATTATCAACAGGAACGTTTTCTAATTTTTTCCATTTCTTCATTGTATTTACAGGAAT
TTTCATCATTATGACCACGATTATCTTGCAGATTATGCGTTATGGTCTATATTCTTCTGTAGATACTACTTTAAAAAATG
CAGCTGACAATGCAAGTGATTACGTCACACGAACAATGGAGCGTAGTGATTCCATACAATCTAATAATAGTTTTAGTAAT
TCTGGAAAAAGTAAACCCAGCTCAAATGTGGCAAGTTTAAGTAATGTCAGTGTGCTACTGTACGATACAAATGGGAAAAT
CGTAAATGCAATTGATGCGTTTGTCCAGTTCGGGACATTAGCATCTAGTGTTGATGAAGACACTATTGGTGAGATTAAAG
ATGAGAAAATGACAACTATCTTTGGTCAAACCGAAAAATACCATGTTTTAACGGTTAGAGTGTATAGTAGTGACTATCCA
ACGATTGAATACGCGACTTTCTTAATCAGTGTTAGTCAGCTTGATGAGGCAAACGAACGTTATGTAACCATAACAGTTTC
AGTCATGATTATTTTCTGGATGATTTCAATTTTAGCAAGTATTTACTTGGCAAATTGGATGCGTAAACCAATTTTAGAAA
GTTATGAAAAACAAAAGCGTTTTGTTGAAAATGCTAGTCACGAATTAAGAACGCCTTTAGCGGTGCTTCAAAACCGACTT
GAAAGTCTTTTTAGACGACCGAATGCAACAATTCTTGATAACAGTGAAAGTATTGCAGCGAGTCTTGACGAAGTTCGTAA
TATGCGTATTTTAACAACCAATCTTTTGAATCTTGCTAGGCGAGATGATGGATTGAAGGTTGAATTAGAAGAAATCCAAC
CTTCAATATTTAATGAAATTTTTGAGAATTACAACATGATTGCCGAAGAAAACGGTAAAACTTTTGTTTCTCATAATTTT
GCGGATCGTCCGATAAAAACTGATCGCACCTTGCTTAAACAATTGATGACAATCTTGTTTGATAATGCGATTAAGTACAC
TGATGATGACGGTTTTATTGAATTTACGGTTAAAACAACAGAACGCCAGACTATTCTAACCGTTGCTGATAATGGACCGG
GTATTAGTGACGCCGATAAAGCGAAAATTTTTGATCGCTTTTATCGCGTTGATAAGGCAAGGACACGTCAAAAAGGTGGC
TTTGGGCTTGGGCTATCTTTAGCTAAACAAATTGTTGATGCCTTAAAAGGTGATATTCAAGTTAAGGATAATCATCCAAA
AGGAACCATATTTGAAGTTCGTTTTAACCGATATAATTTTGGTAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33ALY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.77

98.416

0.588
  ciaH Streptococcus pneumoniae Rx1

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae D39

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae R6

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae TIGR4

52.403

98.869

0.518