Detailed information NTG1023036

Bioinformatically predicted

Overview

• Name: comGD
• Type: Machinery gene
• Locus tag: DQN23_RS00720
• Genome accession: NZ_LS483403
• Coordinates: 107349..107780 (+)
• Length: 143 a.a.
• NCBI ID: WP_020915990.1
• Uniprot ID: A0AB33AJ27
• Organism: Streptococcus lutetiensis strain NCTC13774
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 102349..112780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN23_RS00700 (NCTC13774_00141)	-	104724..105092 (+)	369	WP_020915986.1	DUF1033 family protein	-
DQN23_RS00705 (NCTC13774_00142)	comGA	105164..106105 (+)	942	WP_020915987.1	competence type IV pilus ATPase ComGA	Machinery gene
DQN23_RS00710 (NCTC13774_00143)	comGB	106029..107072 (+)	1044	WP_020915988.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQN23_RS00715 (NCTC13774_00144)	comGC	107072..107365 (+)	294	WP_020915989.1	competence type IV pilus major pilin ComGC	Machinery gene
DQN23_RS00720 (NCTC13774_00145)	comGD	107349..107780 (+)	432	WP_020915990.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQN23_RS00725 (NCTC13774_00146)	comGE	107734..108027 (+)	294	WP_020915991.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQN23_RS00730 (NCTC13774_00147)	comGF	108011..108448 (+)	438	WP_043894883.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQN23_RS00735 (NCTC13774_00148)	comGG	108420..108770 (+)	351	WP_020915993.1	competence type IV pilus minor pilin ComGG	Machinery gene
DQN23_RS00740 (NCTC13774_00149)	comGH	108824..109780 (+)	957	WP_020915994.1	class I SAM-dependent methyltransferase	Machinery gene
DQN23_RS00745 (NCTC13774_00150)	-	109834..111033 (+)	1200	WP_020915995.1	acetate kinase	-
DQN23_RS00750 (NCTC13774_00151)	-	111193..111390 (+)	198	WP_020915996.1	helix-turn-helix transcriptional regulator	-
DQN23_RS00755 (NCTC13774_00152)	-	111407..111607 (+)	201	WP_058814360.1	hypothetical protein	-
DQN23_RS00760 (NCTC13774_00153)	-	111608..112063 (+)	456	WP_231853254.1	ABC transporter permease	-
DQN23_RS00765 (NCTC13774_00154)	-	112078..112713 (+)	636	WP_111712559.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 143 a.a.
• Molecular weight: 16157.52 Da
• Isoelectric Point: 8.7942

>NTDB_id=1023036 DQN23_RS00720 WP_020915990.1 107349..107780(+) (comGD) [Streptococcus lutetiensis strain NCTC13774]
MRLKNKAFYAFTLIESLLTLAISCFMVIMLSGSVNHIFQSVDETLFFLSFENLYRDTQKLASIKQESQTLQISQDAISNG
ITSVKVPKTVLVDKNYQLVFDKSGGNSSLTKIQFHTENQAIDYQLYIGSGNYKKTETKSLHTP

Nucleotide

• Length: 432 bp

>NTDB_id=1023036 DQN23_RS00720 WP_020915990.1 107349..107780(+) (comGD) [Streptococcus lutetiensis strain NCTC13774]
ATGCGGCTAAAAAATAAAGCTTTTTACGCCTTTACCCTTATCGAAAGTTTGCTGACTTTAGCAATTTCTTGTTTTATGGT
CATCATGCTATCAGGTTCGGTCAATCATATTTTTCAATCGGTCGATGAAACTTTGTTCTTTCTTTCCTTTGAAAATCTTT
ATCGCGATACACAAAAATTGGCTAGTATTAAGCAGGAAAGTCAGACTTTGCAGATATCGCAAGATGCGATTTCAAATGGA
ATCACTAGTGTTAAGGTTCCTAAAACTGTATTGGTTGACAAGAATTATCAGCTTGTTTTTGATAAATCAGGGGGTAATTC
ATCTCTTACCAAGATACAGTTTCATACAGAAAACCAGGCAATCGATTATCAATTGTACATAGGAAGTGGTAACTATAAAA
AAACAGAAACTAAAAGCTTACATACTCCTTGA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0AB33AJ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGD	Streptococcus mutans UA140	54.264	90.21	0.49
comGD	Streptococcus mutans UA159	54.264	90.21	0.49
comGD	Streptococcus gordonii str. Challis substr. CH1	45.185	94.406	0.427
comGD/cglD	Streptococcus pneumoniae Rx1	44.615	90.909	0.406
comGD/cglD	Streptococcus pneumoniae D39	44.615	90.909	0.406
comGD/cglD	Streptococcus pneumoniae R6	44.615	90.909	0.406
comGD/cglD	Streptococcus mitis NCTC 12261	44.615	90.909	0.406
comGD/cglD	Streptococcus pneumoniae TIGR4	43.846	90.909	0.399
comGD/cglD	Streptococcus mitis SK321	43.846	90.909	0.399