Detailed information NTG1023005

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: AB2M35_RS13670
• Genome accession: NZ_CP161902
• Coordinates: 2555115..2555732 (-)
• Length: 205 a.a.
• NCBI ID: WP_046160608.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain DYJ22
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2550115..2560732

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB2M35_RS13640 (AB2M35_13640)	rpsT	2550417..2550683 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
AB2M35_RS13645 (AB2M35_13645)	holA	2550698..2551741 (-)	1044	WP_014480310.1	DNA polymerase III subunit delta	-
AB2M35_RS13650 (AB2M35_13650)	-	2551781..2551930 (-)	150	WP_003229985.1	hypothetical protein	-
AB2M35_RS13655 (AB2M35_13655)	yqzM	2551971..2552105 (+)	135	WP_003229983.1	YqzM family protein	-
AB2M35_RS13660 (AB2M35_13660)	comEC	2552145..2554475 (-)	2331	WP_069837640.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AB2M35_RS13665 (AB2M35_13665)	comEB	2554479..2555048 (-)	570	WP_003229978.1	ComE operon protein 2	-
AB2M35_RS13670 (AB2M35_13670)	comEA	2555115..2555732 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
AB2M35_RS13675 (AB2M35_13675)	comER	2555816..2556637 (+)	822	WP_032726195.1	late competence protein ComER	-
AB2M35_RS13680 (AB2M35_13680)	yqeM	2556703..2557446 (-)	744	WP_069837641.1	class I SAM-dependent methyltransferase	-
AB2M35_RS13685 (AB2M35_13685)	rsfS	2557443..2557799 (-)	357	WP_014480315.1	ribosome silencing factor	-
AB2M35_RS13690 (AB2M35_13690)	yqeK	2557817..2558377 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
AB2M35_RS13695 (AB2M35_13695)	nadD	2558367..2558936 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
AB2M35_RS13700 (AB2M35_13700)	yhbY	2558948..2559238 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
AB2M35_RS13705 (AB2M35_13705)	aroE	2559232..2560074 (-)	843	WP_014480317.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21738.48 Da
• Isoelectric Point: 4.7284

>NTDB_id=1023005 AB2M35_RS13670 WP_046160608.1 2555115..2555732(-) (comEA) [Bacillus subtilis strain DYJ22]
MNWLNQHKKAIVLAASAAVFTAIMIFLATGKNKEPVKQAVPTEAENTVVKQEANNDESSETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEEITKVSGIGEKLFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=1023005 AB2M35_RS13670 WP_046160608.1 2555115..2555732(-) (comEA) [Bacillus subtilis strain DYJ22]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTGTTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGGCAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAGCGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGAGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTTTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAAGAAAACGGGCGTTTCCAAACAATTGAAGAAATCACTAAGGT
TTCAGGAATAGGTGAAAAGTTATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (63-118)

• Helix-hairpin-helix motif (HHH_3) (142-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	97.561	100	0.976
comEA	Staphylococcus aureus MW2	35.909	100	0.385
comEA	Staphylococcus aureus N315	35	100	0.376