NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	DQM82_RS09370	Genome accession	NZ_LS483386
Coordinates	1845336..1845932 (-)	Length	198 a.a.
NCBI ID	WP_023612588.1	Uniprot ID	-
Organism	Streptococcus pyogenes strain NCTC13742
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1840336..1850932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM82_RS09335 (NCTC13742_01838)	-	1840395..1840700 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
DQM82_RS09340 (NCTC13742_01839)	ruvX	1840712..1841131 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
DQM82_RS09345 (NCTC13742_01840)	-	1841128..1841397 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
DQM82_RS09350 (NCTC13742_01841)	spx	1841512..1841910 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
DQM82_RS09355 (NCTC13742_01842)	recA	1842201..1843337 (-)	1137	WP_023612576.1	recombinase RecA	Machinery gene
DQM82_RS09360 (NCTC13742_01843)	cinA	1843426..1844697 (-)	1272	WP_023612554.1	competence/damage-inducible protein A	Machinery gene
DQM82_RS09365 (NCTC13742_01844)	-	1844766..1845326 (-)	561	WP_023611248.1	DNA-3-methyladenine glycosylase I	-
DQM82_RS09370 (NCTC13742_01845)	ruvA	1845336..1845932 (-)	597	WP_023612588.1	Holliday junction branch migration protein RuvA	Machinery gene
DQM82_RS09375 (NCTC13742_01846)	-	1845934..1847154 (-)	1221	WP_002992187.1	MDR family MFS transporter	-
DQM82_RS09380 (NCTC13742_01847)	hexB	1847165..1849147 (-)	1983	WP_023612567.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQM82_RS09385 (NCTC13742_01848)	-	1849242..1850393 (-)	1152	WP_003058754.1	tyrosine-type recombinase/integrase	-
DQM82_RS10175	-	1850642..1850785 (+)	144	WP_011185066.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21829.16 Da Isoelectric Point: 6.2537

                                >NTDB_id=1022166 DQM82_RS09370 WP_023612588.1 1845336..1845932(-) (ruvA) [Streptococcus pyogenes strain NCTC13742]

MYDYIKGQLTKLTAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL

LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=1022166 DQM82_RS09370 WP_023612588.1 1845336..1845932(-) (ruvA) [Streptococcus pyogenes strain NCTC13742]

ATGTACGATTATATTAAAGGTCAATTGACCAAACTTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGATGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA

CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

RuvA N terminal domain (RuvA_N)

(1-61)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	41.379	100	0.424

Detailed information NTG1022166