Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   SMUFR_RS09110 Genome accession   NZ_CP007016
Coordinates   1851996..1852289 (-) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   Q8DS53
Organism   Streptococcus mutans UA159-FR     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1846996..1857289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUFR_RS09075 (SMUFR_1713) - 1847004..1847666 (-) 663 WP_002263446.1 type II CAAX endopeptidase family protein -
  SMUFR_RS09080 (SMUFR_1714) - 1847719..1848159 (-) 441 WP_002263445.1 hypothetical protein -
  SMUFR_RS09085 (SMUFR_1715) - 1848128..1848373 (-) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  SMUFR_RS09090 (SMUFR_1716) - 1848942..1850141 (-) 1200 WP_002263443.1 acetate kinase -
  SMUFR_RS09095 (SMUFR_1717) comGH 1850200..1851153 (-) 954 WP_002263442.1 class I SAM-dependent methyltransferase Machinery gene
  SMUFR_RS09100 (SMUFR_1718) comGG 1851208..1851597 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUFR_RS09105 (SMUFR_1719) comGF 1851575..1852009 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMUFR_RS09110 (SMUFR_1720) comGE 1851996..1852289 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUFR_RS09115 (SMUFR_1721) comGD 1852261..1852665 (-) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUFR_RS09120 (SMUFR_1722) comGC 1852652..1852966 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUFR_RS09125 (SMUFR_1723) comGB 1852966..1853997 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUFR_RS09130 (SMUFR_1724) comGA 1853933..1854874 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUFR_RS09135 (SMUFR_1725) - 1855004..1855387 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=102206 SMUFR_RS09110 WP_002263439.1 1851996..1852289(-) (comGE) [Streptococcus mutans UA159-FR]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=102206 SMUFR_RS09110 WP_002263439.1 1851996..1852289(-) (comGE) [Streptococcus mutans UA159-FR]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGGCTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DS53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

100

100

1
  comGE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412

Multiple sequence alignment