Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SMUFR_RS08800 Genome accession   NZ_CP007016
Coordinates   1793998..1795323 (-) Length   441 a.a.
NCBI ID   WP_002262113.1    Uniprot ID   Q8DS94
Organism   Streptococcus mutans UA159-FR     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1788998..1800323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUFR_RS10540 (SMUFR_1653) - 1789397..1789561 (-) 165 WP_002265308.1 hypothetical protein -
  SMUFR_RS10885 - 1790001..1790213 (+) 213 Protein_1687 IS3 family transposase -
  SMUFR_RS08775 (SMUFR_1654) - 1790336..1790740 (-) 405 WP_002263912.1 hypothetical protein -
  SMUFR_RS08780 (SMUFR_1655) - 1790887..1791306 (-) 420 WP_002263913.1 hypothetical protein -
  SMUFR_RS08785 (SMUFR_1657) - 1792687..1793088 (-) 402 WP_002310604.1 hypothetical protein -
  SMUFR_RS08790 (SMUFR_1658) cipB 1793219..1793449 (-) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  SMUFR_RS08795 comC/blpC 1793716..1793856 (+) 141 WP_002267610.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  SMUFR_RS08800 (SMUFR_1659) comD/blpH 1793998..1795323 (-) 1326 WP_002262113.1 sensor histidine kinase Regulator
  SMUFR_RS08805 (SMUFR_1660) comE/blpR 1795320..1796072 (-) 753 WP_002262114.1 response regulator transcription factor Regulator
  SMUFR_RS08810 (SMUFR_1661) - 1796544..1797182 (-) 639 WP_002262115.1 VTT domain-containing protein -
  SMUFR_RS08815 (SMUFR_1662) - 1797229..1797855 (-) 627 WP_002262116.1 hypothetical protein -
  SMUFR_RS08820 (SMUFR_1663) der 1797930..1799240 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  SMUFR_RS08825 (SMUFR_1664) dnaI 1799253..1800152 (-) 900 WP_002262118.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50540.70 Da        Isoelectric Point: 9.8211

>NTDB_id=102198 SMUFR_RS08800 WP_002262113.1 1793998..1795323(-) (comD/blpH) [Streptococcus mutans UA159-FR]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIALSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGTQGIVMGSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQVLYVIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPEMELLDFITILSILCDNAIEAAFESLNPEIQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSNHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=102198 SMUFR_RS08800 WP_002262113.1 1793998..1795323(-) (comD/blpH) [Streptococcus mutans UA159-FR]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTGAACGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGCTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAACTCAAGGAATTGTAATGGGCAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTCAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATTCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGTATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGAGATGGAGTTGCTTGATTTCATTACCATACTTTC
TATCTTGTGTGATAATGCCATTGAGGCTGCTTTCGAATCATTAAATCCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGTATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAATCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DS94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

100

100

1

Multiple sequence alignment