Detailed information NTG1021653

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DQM69_RS10090
• Genome accession: NZ_LS483381
• Coordinates: 2077644..2080205 (-)
• Length: 853 a.a.
• NCBI ID: WP_109982791.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain NCTC10921
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2072644..2085205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM69_RS10065	-	2073167..2073430 (+)	264	WP_109982789.1	hypothetical protein	-
DQM69_RS10070 (NCTC10921_02011)	-	2073480..2073881 (+)	402	WP_019777428.1	helix-turn-helix domain-containing protein	-
DQM69_RS10075 (NCTC10921_02012)	-	2073915..2074466 (-)	552	WP_002960562.1	DNA-3-methyladenine glycosylase I	-
DQM69_RS10080 (NCTC10921_02013)	ruvA	2074635..2075225 (-)	591	WP_019769153.1	Holliday junction branch migration protein RuvA	Machinery gene
DQM69_RS10085 (NCTC10921_02014)	hexB	2075457..2077403 (-)	1947	WP_109982790.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQM69_RS10090 (NCTC10921_02015)	hexA	2077644..2080205 (-)	2562	WP_109982791.1	DNA mismatch repair protein MutS	Machinery gene
DQM69_RS10095 (NCTC10921_02016)	-	2080192..2080545 (-)	354	WP_019787291.1	YlbF family regulator	-
DQM69_RS10100 (NCTC10921_02017)	argR	2080538..2080972 (-)	435	WP_019775054.1	arginine repressor	-
DQM69_RS10105 (NCTC10921_02018)	argS	2081128..2082819 (+)	1692	WP_109982792.1	arginine--tRNA ligase	-
DQM69_RS10110	-	2083032..2083391 (-)	360	WP_002960574.1	hypothetical protein	-
DQM69_RS10115 (NCTC10921_02019)	-	2083430..2083657 (-)	228	WP_002960575.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQM69_RS10120 (NCTC10921_02020)	-	2084226..2085167 (-)	942	WP_019784684.1	YitT family protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 95182.31 Da
• Isoelectric Point: 4.7432

>NTDB_id=1021653 DQM69_RS10090 WP_109982791.1 2077644..2080205(-) (hexA) [Streptococcus sobrinus strain NCTC10921]
MAKDKISPGMQQYLDIKESYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
DLGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSSNNFLVAIDYLNGVYGLSYMDLSTGEFYATSLTDFTA
VRSEIQNLKAKEVVLGFDLSDKQQEALTKQMSLLLSPEKEVYDDVQLIGSDLSSVEAQAAGKLLQYVHQTQKRELSHLQS
LVHYEIKDFLQMTYATKTSLDLLENARSSKKHGSLFWLLDSTKTAMGMRLLRTWIDRPLVSQEKILERQEIVQTFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPKIKTMLASFASPVLDRLNEAIDALPELESLIASAIDQ
DAPATITEGGMIKIGFDQQLDHYRQVMREGTTWIAEIEAKERAASGISTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGDMLEAREQSATLEYDIFMTVRNQVEKYIQRLQDLAKNIATVDALQSLAVVAENNHYVRPQFN
DQEVIDIQDGRHAVVEKVMGTQEYIPNTITLDQDTAIQLITGPNMSGKSTYMRQLALTVVMAQIGSFVAAESANLPIFDA
IYTRIGAADDLISGQSTFMVEMMEANMAIQRASSQSLILFDELGRGTATYDGMALAQAIIEHIHDQVGAKTFFATHYHEL
TELSTSLTHLVNVHVATLEKDGDVTFLHKITAGPADKSYGVHVAKIAGLPEALLQRANAILTDLEAHSVSLTGQEDFTEL
DKPIKQKRDSQQLSLFEVAEPNDKLVQALQDLDVVNMTPMEAMNALFELKKLL

Nucleotide

• Length: 2562 bp

>NTDB_id=1021653 DQM69_RS10090 WP_109982791.1 2077644..2080205(-) (hexA) [Streptococcus sobrinus strain NCTC10921]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAGCAGTATTTAGACATCAAAGAATCCTATCCGGATGCTTTTTTGCTTTT
TCGGATGGGGGATTTTTATGAGCTCTTCTACGACGATGCGGTTAAGGCTGCTCAGATTTTGGAAATCAGCCTCACCAGTC
GCAATAAGAATGCTGACAATCCCATTCCTATGGCGGGCGTGCCCTATCATTCAGCACAACAATATATTGATGTCCTAGTC
GATTTGGGTTATAAGGTGGCCATTGCCGAGCAGATGGAGGACCCCAAAAAGGCTGTTGGTGTCGTCAAACGGGAGGTTGT
TCAGGTGATTACGCCAGGAACCGTGGTGGATTCCAGCAAGCCCGATAGCAGTAATAATTTCTTGGTTGCCATCGACTATC
TGAATGGGGTTTACGGACTCTCCTATATGGACCTCTCAACTGGGGAGTTTTACGCCACCAGCCTGACAGACTTTACAGCC
GTTCGTAGCGAAATTCAAAATCTCAAGGCCAAGGAAGTCGTTCTGGGCTTTGATTTGAGTGACAAGCAGCAGGAAGCTCT
GACCAAGCAGATGAGTCTCCTTTTGTCACCTGAAAAAGAGGTCTATGATGATGTCCAGCTGATTGGCTCTGACTTGTCAA
GCGTAGAGGCCCAGGCCGCTGGTAAGCTCCTCCAATACGTCCATCAGACACAAAAGCGGGAGCTCAGCCACCTACAAAGT
CTGGTTCACTACGAAATCAAGGACTTCCTGCAGATGACCTATGCCACCAAGACCAGTCTGGATCTCTTGGAAAATGCTAG
AAGCAGCAAGAAGCACGGCAGTCTCTTCTGGCTTTTGGATTCAACTAAGACAGCCATGGGGATGCGGCTCTTGCGGACCT
GGATTGATCGGCCCTTGGTTAGCCAAGAGAAAATCTTGGAGCGGCAGGAGATTGTTCAGACCTTCTTGGATAACTTTTTT
GAACGCAGCGACCTGACCGACAGCCTCAAGGGCGTCTATGATATTGAACGCCTGGCCAGCCGAGTGTCTTTTGGTAAGGC
CAATCCCAAGGACCTCTTGCAGTTGGGGCATACTCTAGCCCAGGTTCCCAAAATCAAGACCATGTTGGCTAGCTTTGCTA
GCCCAGTTTTAGACCGGCTAAATGAAGCCATTGATGCCCTGCCGGAGTTGGAAAGTCTGATTGCCTCGGCCATTGACCAA
GATGCTCCAGCCACCATTACCGAAGGGGGCATGATTAAGATAGGCTTTGACCAGCAGTTGGATCATTATCGCCAGGTGAT
GCGGGAAGGAACCACCTGGATTGCCGAAATCGAAGCCAAGGAGCGAGCAGCCAGCGGGATTTCCACCCTCAAGATTGATT
ACAACCGCAAGGATGGTTACTATTTCCATGTGACCAATTCCAATCTTTCCCTAGTGCCGGACCATTTCTTCCGCAAGGCA
ACTCTGAAAAATTCTGAGCGGTTTGGAACTGCTGAACTAGCCAAAATTGAAGGTGATATGCTGGAAGCGAGGGAGCAATC
GGCAACCCTTGAGTACGATATCTTTATGACCGTCCGCAATCAGGTGGAAAAATACATCCAGCGCCTGCAAGACCTGGCTA
AAAATATTGCAACTGTGGATGCTCTGCAAAGTCTAGCTGTTGTCGCTGAAAACAATCATTATGTGCGACCCCAGTTCAAT
GACCAAGAGGTCATTGACATTCAAGACGGTCGCCATGCTGTTGTCGAAAAGGTCATGGGAACCCAGGAATACATCCCCAA
CACCATAACCTTAGACCAGGATACCGCTATTCAGCTGATTACGGGTCCTAATATGAGTGGGAAATCCACCTATATGCGCC
AGCTAGCCCTGACTGTTGTTATGGCCCAAATTGGCTCCTTTGTGGCCGCTGAGTCAGCCAATTTGCCAATTTTTGATGCT
ATCTATACACGGATTGGGGCAGCTGATGACCTGATTTCTGGTCAATCCACCTTCATGGTTGAGATGATGGAGGCCAACAT
GGCCATCCAGCGGGCCAGCAGTCAGTCCCTTATCCTCTTTGATGAATTGGGTCGAGGCACCGCCACCTATGACGGAATGG
CTCTAGCTCAAGCCATTATCGAACACATTCACGACCAGGTAGGGGCTAAGACCTTCTTCGCCACCCACTATCATGAGTTG
ACAGAACTGTCAACTAGCTTGACACACCTAGTTAATGTTCATGTAGCGACTCTGGAAAAGGATGGGGATGTCACCTTCCT
GCATAAGATTACAGCTGGTCCTGCTGACAAGTCTTACGGGGTTCATGTGGCCAAGATTGCAGGTTTGCCTGAGGCTCTCC
TCCAGCGAGCCAATGCTATCTTGACTGATTTAGAGGCCCATTCGGTCAGCTTAACCGGCCAAGAAGACTTTACAGAGCTT
GACAAACCTATCAAACAGAAAAGAGACAGTCAACAGTTGTCCCTCTTTGAAGTAGCAGAACCTAATGATAAGTTGGTTCA
AGCCCTCCAAGACCTTGATGTGGTCAATATGACCCCTATGGAAGCCATGAATGCCCTTTTTGAGTTGAAAAAATTGTTGT
AA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.014	100	0.721
mutS	Pseudomonas stutzeri strain ATCC 17587	38.662	94.607	0.366