Detailed information NTG1020929

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: ABZ559_RS05630
• Genome accession: NZ_CP160400
• Coordinates: 1094494..1095225 (+)
• Length: 243 a.a.
• NCBI ID: WP_367007494.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZY19097
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1092564..1093766	1094494..1095225	flank	728

Gene organization within MGE regions

Location: 1092564..1095225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABZ559_RS05620 (ABZ559_05620)	-	1092564..1093766 (-)	1203	WP_367007018.1	IS110 family transposase	-
ABZ559_RS05625 (ABZ559_05625)	-	1094151..1094477 (+)	327	WP_273415047.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
ABZ559_RS05630 (ABZ559_05630)	comE/comE1	1094494..1095225 (+)	732	WP_367007494.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28368.50 Da
• Isoelectric Point: 5.9228

>NTDB_id=1020929 ABZ559_RS05630 WP_367007494.1 1094494..1095225(+) (comE/comE1) [Streptococcus sp. ZY19097]
MLDIYVLEDNITQQFRMEREIETIMAKNHWDYQRIEVFSSANEIIAKATEKGEHQIFFLDLEIKDDEKQGIDVAKAIREK
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERLELCLKEAMKHKIGNFGENSFLFETSKARVRVPYSDIL
YFETSSAVHRMILHTKNDRIEFYATIAEVAKSDKRLFKCHRSFIINVDNVVRFDKATRSIYFETGDTCLVSRDKVKPLLN
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=1020929 ABZ559_RS05630 WP_367007494.1 1094494..1095225(+) (comE/comE1) [Streptococcus sp. ZY19097]
ATGTTAGATATTTATGTACTAGAGGATAATATCACACAACAATTTCGTATGGAACGCGAGATTGAGACCATTATGGCGAA
AAATCATTGGGATTATCAGAGGATAGAAGTGTTTAGTTCTGCAAATGAGATTATAGCAAAGGCAACTGAAAAAGGAGAAC
ACCAAATTTTCTTTCTGGATTTAGAGATCAAAGACGATGAAAAGCAAGGAATTGATGTCGCTAAAGCTATTCGTGAAAAA
GATGCGACAGCTATCATTGTTTTTGTAACAACCCATTCAGAATTTATGTTGTTAACTTATCAAGCGTTAGTGGGGGCGAT
TGATTTTATTGATAAGAATTTGAACGACCAGGCATTTAGCGAACGCTTAGAGTTGTGCTTGAAAGAAGCCATGAAACATA
AAATTGGTAATTTTGGAGAAAATTCCTTTTTATTTGAGACTTCCAAAGCACGTGTACGTGTTCCATATAGTGACATTCTT
TATTTTGAAACATCTTCTGCTGTGCACCGCATGATTTTACATACGAAAAATGACAGAATAGAATTTTATGCGACGATTGC
AGAGGTTGCTAAATCAGACAAGCGTCTTTTCAAGTGCCATCGTTCTTTTATCATTAATGTGGATAATGTGGTCAGATTTG
ATAAAGCCACACGAAGTATTTATTTTGAAACAGGCGATACTTGCCTAGTTTCGAGAGATAAAGTAAAACCTCTATTGAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-238)

• Response regulator receiver domain (Response_reg) (5-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	73.663	100	0.737
comE/blpR	Streptococcus mutans UA159	48.536	98.354	0.477
comE/comE2	Streptococcus equinus JB1	46.694	99.588	0.465