NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	DQM46_RS09325	Genome accession	NZ_LS483357
Coordinates	1812746..1813342 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain NCTC8326
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1807746..1818342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM46_RS09290 (NCTC8326_01854)	-	1807806..1808111 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
DQM46_RS09295 (NCTC8326_01855)	ruvX	1808123..1808542 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
DQM46_RS09300 (NCTC8326_01856)	-	1808539..1808808 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
DQM46_RS09305 (NCTC8326_01857)	spx	1808922..1809320 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
DQM46_RS09310 (NCTC8326_01858)	recA	1809611..1810747 (-)	1137	WP_002992179.1	recombinase RecA	-
DQM46_RS09315 (NCTC8326_01859)	cinA	1810836..1812107 (-)	1272	WP_002992182.1	competence/damage-inducible protein A	Machinery gene
DQM46_RS09320 (NCTC8326_01860)	-	1812176..1812736 (-)	561	WP_002992183.1	DNA-3-methyladenine glycosylase I	-
DQM46_RS09325 (NCTC8326_01861)	ruvA	1812746..1813342 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
DQM46_RS09330 (NCTC8326_01862)	-	1813344..1814564 (-)	1221	WP_011529098.1	MDR family MFS transporter	-
DQM46_RS09335 (NCTC8326_01863)	hexB	1814575..1816557 (-)	1983	WP_021299132.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQM46_RS09340 (NCTC8326_01864)	-	1816652..1817797 (-)	1146	WP_021299091.1	tyrosine-type recombinase/integrase	-
DQM46_RS10060	-	1818000..1818143 (+)	144	WP_011185066.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=1020111 DQM46_RS09325 WP_002992186.1 1812746..1813342(-) (ruvA) [Streptococcus pyogenes strain NCTC8326]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=1020111 DQM46_RS09325 WP_002992186.1 1812746..1813342(-) (ruvA) [Streptococcus pyogenes strain NCTC8326]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG1020111