Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   DQL39_RS08765 Genome accession   NZ_LS483353
Coordinates   1714372..1714968 (+) Length   198 a.a.
NCBI ID   WP_011185063.1    Uniprot ID   A2RGV1
Organism   Streptococcus pyogenes strain NCTC4001     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1709372..1719968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL39_RS08755 (NCTC4001_01730) hexB 1711157..1713139 (+) 1983 WP_038433760.1 DNA mismatch repair endonuclease MutL Machinery gene
  DQL39_RS08760 (NCTC4001_01731) - 1713150..1714370 (+) 1221 WP_011018316.1 MDR family MFS transporter -
  DQL39_RS08765 (NCTC4001_01732) ruvA 1714372..1714968 (+) 597 WP_011185063.1 Holliday junction branch migration protein RuvA Machinery gene
  DQL39_RS08770 (NCTC4001_01733) - 1714978..1715538 (+) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  DQL39_RS08775 (NCTC4001_01734) cinA 1715607..1716878 (+) 1272 WP_038433761.1 competence/damage-inducible protein A Machinery gene
  DQL39_RS08780 (NCTC4001_01735) recA 1716967..1718103 (+) 1137 WP_002992179.1 recombinase RecA Machinery gene
  DQL39_RS08785 (NCTC4001_01736) spx 1718394..1718792 (+) 399 WP_002982188.1 transcriptional regulator Spx -
  DQL39_RS08790 (NCTC4001_01737) - 1718905..1719174 (+) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  DQL39_RS08795 (NCTC4001_01738) ruvX 1719171..1719590 (+) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  DQL39_RS08800 (NCTC4001_01739) - 1719602..1719907 (+) 306 WP_002982199.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21852.19 Da        Isoelectric Point: 6.4948

>NTDB_id=1019825 DQL39_RS08765 WP_011185063.1 1714372..1714968(+) (ruvA) [Streptococcus pyogenes strain NCTC4001]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=1019825 DQL39_RS08765 WP_011185063.1 1714372..1714968(+) (ruvA) [Streptococcus pyogenes strain NCTC4001]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGCATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAACAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RGV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae R6

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae D39

66.497

99.495

0.662
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.394

100

0.414