Detailed information NTG1019792

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL39_RS06060
• Genome accession: NZ_LS483353
• Coordinates: 1184255..1185256 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain NCTC4001
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1179255..1190256

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL39_RS06045 (NCTC4001_01210)	thrS	1179425..1181368 (-)	1944	WP_038433659.1	threonine--tRNA ligase	-
DQL39_RS06050 (NCTC4001_01212)	-	1181790..1183124 (-)	1335	WP_038433660.1	glycosyltransferase family 4 protein	-
DQL39_RS06055 (NCTC4001_01213)	-	1183126..1184124 (-)	999	WP_038433661.1	glycosyltransferase family 4 protein	-
DQL39_RS06060 (NCTC4001_01214)	ccpA	1184255..1185256 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL39_RS06065 (NCTC4001_01215)	-	1185430..1186515 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQL39_RS06070 (NCTC4001_01216)	-	1186564..1187229 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQL39_RS06075 (NCTC4001_01217)	-	1187240..1187617 (+)	378	WP_002985686.1	VOC family protein	-
DQL39_RS06080 (NCTC4001_01218)	-	1187762..1188688 (+)	927	WP_038433663.1	glycosyltransferase family 2 protein	-
DQL39_RS06085 (NCTC4001_01219)	-	1188899..1189582 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1019792 DQL39_RS06060 WP_002985680.1 1184255..1185256(-) (ccpA) [Streptococcus pyogenes strain NCTC4001]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1019792 DQL39_RS06060 WP_002985680.1 1184255..1185256(-) (ccpA) [Streptococcus pyogenes strain NCTC4001]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGCCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGATTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559