Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   DQM50_RS04290 Genome accession   NZ_LS483347
Coordinates   793752..794714 (+) Length   320 a.a.
NCBI ID   WP_085613984.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8324     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 788752..799714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM50_RS04270 (NCTC8324_00863) - 789461..790681 (-) 1221 WP_085613980.1 DUF3114 domain-containing protein -
  DQM50_RS04275 (NCTC8324_00864) queA 790688..791716 (-) 1029 WP_085613981.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  DQM50_RS04280 (NCTC8324_00865) nagB 791918..792622 (+) 705 WP_085613982.1 glucosamine-6-phosphate deaminase -
  DQM50_RS04285 (NCTC8324_00866) - 792741..793457 (+) 717 WP_085613983.1 pseudouridine synthase -
  DQM50_RS04290 (NCTC8324_00867) coiA 793752..794714 (+) 963 WP_085613984.1 competence protein CoiA Machinery gene
  DQM50_RS04295 (NCTC8324_00868) pepF 794727..796532 (+) 1806 WP_085613985.1 oligoendopeptidase F Regulator
  DQM50_RS04300 (NCTC8324_00869) - 796908..798104 (+) 1197 WP_002995765.1 OFA family MFS transporter -
  DQM50_RS04305 (NCTC8324_00870) - 798170..798877 (+) 708 WP_002989211.1 O-methyltransferase -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37827.33 Da        Isoelectric Point: 10.2848

>NTDB_id=1019191 DQM50_RS04290 WP_085613984.1 793752..794714(+) (coiA) [Streptococcus pyogenes strain NCTC8324]
MTKILTALDGKNQLISLVTQPILTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=1019191 DQM50_RS04290 WP_085613984.1 793752..794714(+) (coiA) [Streptococcus pyogenes strain NCTC8324]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTTAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACTATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAGAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTACAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(23-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

43.548

96.875

0.422
  coiA Streptococcus pneumoniae Rx1

42.258

96.875

0.409
  coiA Streptococcus pneumoniae D39

42.258

96.875

0.409
  coiA Streptococcus pneumoniae R6

42.258

96.875

0.409
  coiA Streptococcus pneumoniae TIGR4

42.258

96.875

0.409
  coiA Lactococcus lactis subsp. cremoris KW2

39.755

100

0.406

Multiple sequence alignment