Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   DQL04_RS08855 Genome accession   NZ_LS483340
Coordinates   1745108..1745704 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain NCTC12062     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1740108..1750704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL04_RS08820 (NCTC12062_01748) - 1740168..1740473 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  DQL04_RS08825 (NCTC12062_01749) ruvX 1740485..1740904 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  DQL04_RS08830 (NCTC12062_01750) - 1740901..1741170 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  DQL04_RS08835 (NCTC12062_01751) spx 1741284..1741682 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  DQL04_RS08840 (NCTC12062_01752) recA 1741973..1743109 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  DQL04_RS08845 (NCTC12062_01753) cinA 1743198..1744469 (-) 1272 WP_111698655.1 competence/damage-inducible protein A Machinery gene
  DQL04_RS08850 (NCTC12062_01754) - 1744538..1745098 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  DQL04_RS08855 (NCTC12062_01755) ruvA 1745108..1745704 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  DQL04_RS08860 (NCTC12062_01756) - 1745706..1746926 (-) 1221 WP_047236048.1 MDR family MFS transporter -
  DQL04_RS08865 (NCTC12062_01757) hexB 1746937..1748919 (-) 1983 WP_047236089.1 DNA mismatch repair endonuclease MutL Machinery gene
  DQL04_RS08870 (NCTC12062_01758) - 1749014..1750159 (-) 1146 WP_111690858.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=1018716 DQL04_RS08855 WP_002992186.1 1745108..1745704(-) (ruvA) [Streptococcus pyogenes strain NCTC12062]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=1018716 DQL04_RS08855 WP_002992186.1 1745108..1745704(-) (ruvA) [Streptococcus pyogenes strain NCTC12062]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment