Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   DQM35_RS06685 Genome accession   NZ_LS483338
Coordinates   1303598..1304296 (+) Length   232 a.a.
NCBI ID   WP_085613747.1    Uniprot ID   O31050
Organism   Streptococcus pyogenes strain NCTC12064     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1298598..1309296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM35_RS06665 (NCTC12064_01320) - 1299900..1302683 (-) 2784 WP_111679857.1 type 2 lanthipeptide synthetase LanM family protein -
  DQM35_RS06670 (NCTC12064_01321) - 1302704..1302859 (-) 156 WP_023612118.1 lacticin 481 family lantibiotic -
  DQM35_RS06675 (NCTC12064_01322) - 1303059..1303214 (-) 156 WP_085613746.1 lacticin 481 family lantibiotic -
  DQM35_RS06680 (NCTC12064_01323) - 1303245..1303400 (-) 156 WP_023612114.1 lacticin 481 family lantibiotic -
  DQM35_RS06685 (NCTC12064_01324) scnR 1303598..1304296 (+) 699 WP_085613747.1 response regulator transcription factor Regulator
  DQM35_RS06690 (NCTC12064_01325) - 1304314..1305675 (+) 1362 WP_085613748.1 sensor histidine kinase KdpD -
  DQM35_RS06695 (NCTC12064_01326) - 1305892..1306407 (-) 516 WP_331844258.1 helical hairpin domain-containing protein -
  DQM35_RS06700 - 1306427..1307553 (+) 1127 WP_111679859.1 IS3 family transposase -
  DQM35_RS08945 (NCTC12064_01329) - 1308166..1308717 (-) 552 WP_226313739.1 portal protein -
  DQM35_RS09065 - 1308694..1308828 (-) 135 Protein_1234 portal protein -
  DQM35_RS09235 (NCTC12064_01331) - 1309022..1309153 (-) 132 WP_002991616.1 hypothetical protein -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 26246.39 Da        Isoelectric Point: 6.1274

>NTDB_id=1018490 DQM35_RS06685 WP_085613747.1 1303598..1304296(+) (scnR) [Streptococcus pyogenes strain NCTC12064]
MNFESQLLNKRILIVDDDVALSKSIKEVLISRDFKNISCAYSISEGIDIFSVSKIDLIILDVMLPDGEGHLLAKYIRKYS
DVPILFLTAKNNPDDEIRGLESGGDDYVTKPFLPKSLTYRIIALLRRAYKDESELIELTNCTIDLNNASVEKNGQHLSLT
PTEIQILRKLFSNKNYIASTESICDTVWGLESLGYEKSLMVHIRNIREKIEITPSKPNHLITVKGLGYKLVI

Nucleotide


Download         Length: 699 bp        

>NTDB_id=1018490 DQM35_RS06685 WP_085613747.1 1303598..1304296(+) (scnR) [Streptococcus pyogenes strain NCTC12064]
ATGAATTTTGAGTCTCAATTATTGAATAAACGCATATTGATTGTCGACGATGATGTCGCACTTAGCAAATCAATTAAAGA
GGTACTTATCAGTCGGGATTTCAAGAATATCAGCTGTGCTTATAGTATAAGCGAAGGAATTGATATCTTCTCAGTTTCTA
AAATTGATCTCATTATTTTAGATGTTATGCTACCAGATGGAGAAGGGCACTTACTTGCAAAATACATTAGGAAATATTCA
GATGTGCCAATTCTCTTTTTAACAGCCAAAAACAATCCTGATGATGAAATTCGAGGACTTGAATCCGGAGGGGATGATTA
TGTTACGAAGCCATTTCTTCCCAAATCTTTAACATATCGTATTATTGCACTGTTGAGAAGGGCTTATAAAGATGAATCGG
AACTAATTGAGCTAACAAATTGTACCATAGACTTAAACAATGCAAGTGTTGAAAAAAATGGTCAACATTTGTCACTCACT
CCAACAGAAATACAAATCCTACGAAAATTATTTTCAAATAAAAATTATATTGCATCAACTGAATCGATTTGTGATACCGT
TTGGGGACTTGAGAGCCTTGGCTACGAAAAATCACTTATGGTACATATTCGCAATATCAGAGAAAAAATCGAGATAACTC
CATCTAAGCCAAATCATCTTATTACTGTAAAAGGGCTTGGTTATAAACTAGTTATATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-230)

Response regulator receiver domain (Response_reg)

(12-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O31050

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

40.948

100

0.409
  vicR Streptococcus mutans UA159

38.528

99.569

0.384
  micA Streptococcus pneumoniae Cp1015

37.826

99.138

0.375