NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	DQL44_RS09625	Genome accession	NZ_LS483335
Coordinates	1838454..1839050 (-)	Length	198 a.a.
NCBI ID	WP_111677540.1	Uniprot ID	-
Organism	Streptococcus pyogenes strain NCTC8332
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1833454..1844050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL44_RS09590 (NCTC8332_01917)	-	1833514..1833819 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
DQL44_RS09595 (NCTC8332_01918)	ruvX	1833831..1834250 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
DQL44_RS09600 (NCTC8332_01919)	-	1834247..1834516 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
DQL44_RS09605 (NCTC8332_01920)	spx	1834630..1835028 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
DQL44_RS09610 (NCTC8332_01921)	recA	1835319..1836455 (-)	1137	WP_111677538.1	recombinase RecA	Machinery gene
DQL44_RS09615 (NCTC8332_01922)	cinA	1836544..1837815 (-)	1272	WP_111677539.1	competence/damage-inducible protein A	Machinery gene
DQL44_RS09620 (NCTC8332_01923)	-	1837884..1838444 (-)	561	WP_011018314.1	DNA-3-methyladenine glycosylase I	-
DQL44_RS09625 (NCTC8332_01924)	ruvA	1838454..1839050 (-)	597	WP_111677540.1	Holliday junction branch migration protein RuvA	Machinery gene
DQL44_RS09630 (NCTC8332_01925)	-	1839052..1840272 (-)	1221	WP_002982178.1	MDR family MFS transporter	-
DQL44_RS09635 (NCTC8332_01926)	hexB	1840283..1842265 (-)	1983	WP_111677601.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQL44_RS09640 (NCTC8332_01927)	-	1842360..1843505 (-)	1146	WP_021775554.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21859.18 Da Isoelectric Point: 6.2537

                                >NTDB_id=1018219 DQL44_RS09625 WP_111677540.1 1838454..1839050(-) (ruvA) [Streptococcus pyogenes strain NCTC8332]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKTRSNKAGNTQLDEAIEAL

LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=1018219 DQL44_RS09625 WP_111677540.1 1838454..1839050(-) (ruvA) [Streptococcus pyogenes strain NCTC8332]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGAG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTAATACCAAAACGCGCAGTAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA

CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	41.379	100	0.424

Detailed information NTG1018219