Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   DQL25_RS09085 Genome accession   NZ_LS483330
Coordinates   1782466..1784448 (-) Length   660 a.a.
NCBI ID   WP_111703701.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8328     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1777466..1789448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL25_RS09060 (NCTC8328_01801) recA 1777502..1778638 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  DQL25_RS09065 (NCTC8328_01802) cinA 1778727..1779998 (-) 1272 WP_032459984.1 competence/damage-inducible protein A Machinery gene
  DQL25_RS09070 (NCTC8328_01803) - 1780067..1780627 (-) 561 WP_111703697.1 DNA-3-methyladenine glycosylase I -
  DQL25_RS09075 (NCTC8328_01804) ruvA 1780637..1781233 (-) 597 WP_038434336.1 Holliday junction branch migration protein RuvA Machinery gene
  DQL25_RS09080 (NCTC8328_01805) - 1781235..1782455 (-) 1221 WP_111703699.1 MDR family MFS transporter -
  DQL25_RS09085 (NCTC8328_01806) hexB 1782466..1784448 (-) 1983 WP_111703701.1 DNA mismatch repair endonuclease MutL Machinery gene
  DQL25_RS09090 (NCTC8328_01807) - 1784543..1785688 (-) 1146 WP_111703703.1 tyrosine-type recombinase/integrase -
  DQL25_RS09840 - 1785943..1786086 (+) 144 WP_011185066.1 putative holin-like toxin -
  DQL25_RS09100 (NCTC8328_01809) irvR 1786947..1787714 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  DQL25_RS09105 (NCTC8328_01810) - 1787868..1788074 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  DQL25_RS09110 (NCTC8328_01811) - 1788108..1788875 (+) 768 WP_080277853.1 Bro-N domain-containing protein -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74373.92 Da        Isoelectric Point: 5.7605

>NTDB_id=1017727 DQL25_RS09085 WP_111703701.1 1782466..1784448(-) (hexB) [Streptococcus pyogenes strain NCTC8328]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLAISNADLDFEVSGYVSLP
ELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAVDNSIKVEK
TELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=1017727 DQL25_RS09085 WP_111703701.1 1782466..1784448(-) (hexB) [Streptococcus pyogenes strain NCTC8328]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCGTTGAAATTGAAGAGTCTGGCCTTAAGA
TGATACAGGTTACAGACAACGGTGAGGGAATGTCTCATGAAGATTTACCTTTAAGTCTGCGTCGCCACGCTACTAGTAAA
ATTAAGAGTCAGAGTGATTTGTTTAGAATTAGAACACTTGGCTTCCGTGGAGAGGCTTTACCGTCTGTTGCCTCTATCAG
TAAAATCACGATAAAAACAGCAACAAAAGAAGTCACTCACGGATCTCTTCTTATAGCTACTGGTGGGGAAATTGAGACAC
TTGAAGCGATCTCAACTCCTACTGGAACCAAAATTAAGGTTGAAAACCTTTTTTACAACACGCCTGCTCGTCTCAAATAT
ATGAAAAGTTTACAGGCAGAATTAGCTCATATTGTAGATGTGGTCAACCGGTTGAGTTTGGCACATCCAGAAGTTGCTTT
CACACTGATTAGTGATGGTCGCCAATTAACTCAGACATCAGGAACTGGCGATTTACGCCAAGCAATTGCAGGGATTTATG
GTTTGAATACTACCAAAAAAATGCTGGCTATCTCTAATGCTGATTTGGATTTTGAAGTTTCCGGCTATGTTAGCTTGCCA
GAGTTGACACGCGCCAACCGTAATTACATGACGATTTTGGTTAATGGGCGTTACATCAAGAATTTCTTGCTTAATCGAGC
AATTCTTGATGGTTACGGTTCTAAGCTCATGGTTGGACGTTTCCCAATTGTTGTGATTGATATTCAGATTGATCCCTATT
TGGCCGATGTCAATGTTCATCCCACAAAACAAGAGGTTCGTATTTCAAAAGAGCGTGAATTAATGGCTTTAATTAGCACG
GCTATTTCAGAGAGTCTTAAGGAACAAGATTTGATTCCAGATGCTCTGGAAAACTTAGCCAAATCAAGCACACGACATTT
CTCTAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGACTTTATTATGATCCTCAAAAGAATGACTTTTTTGTCA
AAGAGTCGGCTGTCTCTGAAAAAATACCTGAAACTGATTTTTATTCCGGCGCTGTTGACAACAGTATAAAGGTTGAAAAA
ACAGAGCTGTTACCCCACTCAGAAGAAGTTATAGGACCTTCTTCGGTTAAACACGCAAGTCGTCCCCAGAATACCTTTAC
CGAGACTGATCATCCTAATCTTGACTTAAAAAACAGACAAAAGTTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
AATCAGTATTTCCCGAATTGGATTATTTTGGTCAGATGCACGGAACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAGCTGTTGGTGCCTTATTTGTTTGAGTTTTCTGGTTCTGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCTTAGAAGTTTATGGGCACAATACTTTCATTTTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTCTCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTGGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCTGTATTGATTAATTTTAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGAATTCAAGAAAATCACACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

67.273

100

0.673