Detailed information NTG1017728

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DQL25_RS09100
• Genome accession: NZ_LS483330
• Coordinates: 1786947..1787714 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8328
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1781947..1792714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL25_RS09085 (NCTC8328_01806)	hexB	1782466..1784448 (-)	1983	WP_111703701.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQL25_RS09090 (NCTC8328_01807)	-	1784543..1785688 (-)	1146	WP_111703703.1	tyrosine-type recombinase/integrase	-
DQL25_RS09840	-	1785943..1786086 (+)	144	WP_011185066.1	putative holin-like toxin	-
DQL25_RS09100 (NCTC8328_01809)	irvR	1786947..1787714 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
DQL25_RS09105 (NCTC8328_01810)	-	1787868..1788074 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DQL25_RS09110 (NCTC8328_01811)	-	1788108..1788875 (+)	768	WP_080277853.1	Bro-N domain-containing protein	-
DQL25_RS09115 (NCTC8328_01812)	-	1788885..1789508 (+)	624	WP_065355060.1	Bro-N domain-containing protein	-
DQL25_RS09120 (NCTC8328_01813)	-	1789535..1789777 (+)	243	WP_000648623.1	hypothetical protein	-
DQL25_RS09125 (NCTC8328_01814)	-	1790036..1790209 (+)	174	WP_000132665.1	hypothetical protein	-
DQL25_RS09130 (NCTC8328_01815)	-	1790427..1790600 (+)	174	WP_000074663.1	plasmid mobilization protein	-
DQL25_RS09965 (NCTC8328_01816)	-	1790920..1791120 (+)	201	WP_001284397.1	hypothetical protein	-
DQL25_RS09140 (NCTC8328_01817)	-	1791222..1791554 (+)	333	WP_011285276.1	hypothetical protein	-
DQL25_RS09145 (NCTC8328_01818)	-	1791554..1791745 (+)	192	WP_021340709.1	hypothetical protein	-
DQL25_RS09150 (NCTC8328_01819)	-	1791757..1792086 (+)	330	WP_003058810.1	hypothetical protein	-
DQL25_RS09155 (NCTC8328_01820)	-	1792089..1792361 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=1017728 DQL25_RS09100 WP_003058809.1 1786947..1787714(-) (irvR) [Streptococcus pyogenes strain NCTC8328]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=1017728 DQL25_RS09100 WP_003058809.1 1786947..1787714(-) (irvR) [Streptococcus pyogenes strain NCTC8328]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4